环境与职业医学2025，Vol.42Issue(3)：334-341,8.DOI:10.11836/JEOM24305
中国南方成年人群室外夜间灯光暴露与阻塞性睡眠呼吸暂停的横断面关联研究
Association of outdoor light at night with obstructive sleep apnoea:A cross-sectional study among adults in Southern China
摘要
Abstract
[Background]Obstructive sleep apnea(OSA)is a sleep disorder characterized by recurrent episodes of obstruction of the upper airway during sleep.Given the substantial number of OSA patients,it is urgently in need to address the burden on society.Current available evidence linking outdoor light at night(LAN)to OSA is scarce. [Objective]To explore the relationships regarding outdoor LAN and OSA among residents in Southern China. [Methods]A total of 3 925 hospitalized patients in Guangdong Provincial People's Hospital Sleep Center were recruited between January 1,2005 and December 31,2015.The severity of OSA was determined by apnea-hypopnea index(AHI)using polysomnography or home sleep test.The annual Suomi National Polar-orbiting Partnership Visible Infrared Imaging Radiometer Suite(NPP-VIIRS)-like LAN data with a 500 m spatial resolution were used to evaluate outdoor LAN levels of the participants 1,3,and 5 years before undergoing sleep monitoring.Generalized linear regression models were utilized to examine the associations of outdoor LAN with OSA. [Results]The ORs(95％CIs)of OSA,mild OSA,and moderate OSA were 1.175(1.021,1.351),1.215(1.038,1.421),and 1.195(1.003,1.425)respectively for per interquartile range(IQR)increment in three-year average outdoor LAN.The results of stratified analyses showed a higher OR of 1.933(95％CI:1.424,2.637)in female than male participants(P interaction＜0.001).Additionally,the ORs of OSA did not sub-stantially change using one-year/five-year instead of three-year average outdoor LAN. [Conclusion]Our findings demonstrate that an elevated outdoor LAN is significantly associated with higher odds of OSA(especially mild and moderate OSA)in Southern China,especially in females.An effective outdoor LAN management and policy-making framework has been suggested as potential preventive measures to reduce burden of OSA.关键词
室外夜间灯光/睡眠障碍/阻塞性睡眠呼吸暂停/呼吸暂停低通气指数Key words
outdoor light at night/sleep disorder/obstructive sleep apnoea/apnea hypopnea index分类
医药卫生引用本文复制引用
王素菡,陈功博,陈艳,熊海林,欧琼..中国南方成年人群室外夜间灯光暴露与阻塞性睡眠呼吸暂停的横断面关联研究[J].环境与职业医学,2025,42(3):334-341,8.基金项目
广州市科技计划-基础与应用基础研究项目(202201011092) （202201011092）
