四川精神卫生2025，Vol.38Issue(2)：131-137,7.DOI:10.11886/scjsws20240813003
四川省泸州市严重精神障碍患者管理现状及病情的影响因素分析
Management status and influencing factors of disease stabilization in patients with severe mental disorders in Luzhou City,Sichuan Province
摘要
Abstract
Background Severe mental disorders represent a major public health concern due to the high disability rates and substantial disease burden,which has garnered significant national attention and prompted their inclusion in public health project management systems.However,credible evidence regarding the current status of disease management and factors influencing disease stabilization among patients with severe mental disorders in Luzhou City,Sichuan Province,remains limited.Objective To investigate the current management status of patients with severe mental disorders in Luzhou City,Sichuan Province,and to analyze influencing factors of disease stabilization among patients under standardized care,so as to provide evidence-based insights for developing targeted management strategies to optimize clinical interventions for this patient population.Methods In March 2023,data were extracted from the Sichuan Mental Health Service Comprehensive Management Platform for patients with severe mental disorders in Luzhou City who received management between December 2017 and December 2022.Information on mental health service utilization and clinical status changes was collected.Trend analysis was conducted to evaluate temporal changes in key management indicators for severe mental disorders in Luzhou City.Logistic regression analysis was employed to identify factors influencing the disease stabilization or fluctuation of these patients.Results This study enrolled a total of 20 232 patients.In Luzhou City,the stabilization rate and standardized management rate of severe mental disorders were 94.89%and 79.36%in 2017,respectively,which increased to 95.33%and 96.92%by 2022.The regular medication adherence rate rose from 34.42%in 2018 to 86.81%in 2022.In 2022,the regular medication adherence rate was 71.80%for schizophrenia,55.26%for paranoid psychosis,and 51.43%for schizoaffective disorder.Multivariate analysis identified the following protective factors for disease stabilization:age of 18～39 years(OR=0.613,95%CI:0.409～0.918),age of 40～65 years(OR=0.615,95%CI:0.407～0.931),urban residence(OR=0.587,95%CI:0.478～0.720),and regular medication adherence(OR=0.826,95%CI:0.702～0.973).Risk factors for disease fluctuation included poor(OR=1.712,95%CI:1.436～2.040),non-inclusion in care-support programs(OR=1.928,95%CI:1.694～2.193),non-participation in community rehabilitation(OR=2.255,95%CI:1.930～2.634),and intermittent medication adherence(OR=3.893,95%CI:2.548～5.946).Conclusion The stability rate,standardized management rate,and regular medication adherence rate of patients with severe mental disorders in Luzhou City have shown a year-by-year increase.Age,household registration status,economic condition,medication compliance,and community-based rehabilitation were identified as influencing factors for disease fluctuation in these patients.[Funded by Luzhou Science and Technology Plan Project(number,2022-ZRK-186)]关键词
严重精神障碍/管理指标/服药依从性/病情波动Key words
Severe mental disorders/Healthcare management indicators/Medication adherence/Symptomatic fluctuation分类
临床医学引用本文复制引用
张雪梅,李博,蔡本静,谭友果,向波,何静,姜启栋,唐坚..四川省泸州市严重精神障碍患者管理现状及病情的影响因素分析[J].四川精神卫生,2025,38(2):131-137,7.基金项目
泸州市科技计划项目(项目名称:川南地区严重精神障碍患者现状分析,项目编号:2022-ZRK-186) （项目名称:川南地区严重精神障碍患者现状分析,项目编号:2022-ZRK-186）
