皮肤性病诊疗学杂志2025，Vol.32Issue(4)：263-269,7.DOI:10.3969/j.issn.1674-8468.2025.04.006
寻常型银屑病合并慢性病患者治疗负担的影响因素分析
Analysis of factors influencing the treatment burden in patients with chronic diseases com-plicated with psoriasis vulgaris
摘要
Abstract
Objective To investigate the current status and influencing factors of treatment burden in patients with psoriasis vulgaris and chronic diseases,providing a basis for optimizing di-agnostic and treatment strategies.Methods A total of 158 patients with psoriasis vulgaris and chronic diseases treated at Dermatology Hospital,Southern Medical University from March 2022 to March 2024,were included in this study.The multimorbidity treatment burden questionnaire(MTBQ)was used to assess treatment burden.The differences in medication use,occupational labor intensity,and residential location were compared between patients with a moderate-to-high burden and those with low or no burden.The perceived social support questionnaire was used to e-valuate social support scores,and the psoriasis area and severity index(PASI)was used to assess disease severity.Univariate and multivariate logistic regression analyses were conducted to identify factors influencing treatment burden.Results Among 158 patients,116(73.42％)reported moderate-to-high treatment burden and 42(26.58％)reported low or no treatment burden.There were significant differences between the moderate-to-high burden group and the low or no burden group in terms of age,gender,medication types,educational level,average monthly household income per capita,medical insurance type,employment status,smoking rate,drinking rate,labor intensity,residential location,PASI score,and social support questionnaire score.Logistics re-gression analysis showed that social support was an independent protective factor against treatment burden(OR=0.94,95％CI:O.90～0.99,P=0.010).The risk of treatment burden increased by 6.33 times for high-intensity laborers,while living in urban areas was an independent protective factor against the treatment burden(OR=0.14,95％CI:0.02～0.98,P=0.040).PASI scores were not significantly associated with treatment burden(P=0.907).Conclusions Patients with psoriasis vulgaris complicated with chronic diseases experience a heavy treatment burden.Higher levels of social support can reduce the risk of treatment burden,while the treatment burden risk increases for individuals engaged in moderate or high-intensity labor.Urban residents have a rela-tively lower treatment burden.Policymakers may consider enhancing social support systems,opti-mizing the allocation of medical resources,and paying particular attention to the healthcare needs of those in high-intensity labor to reduce their treatment burden.关键词
寻常型银屑病/慢性病/治疗负担/社会支持/PASI评分Key words
psoriasis vulgaris/chronic diseases/treatment burden/social support/PA-SI score引用本文复制引用
徐俊芳,秦瑶,曹硕,陈雪梅..寻常型银屑病合并慢性病患者治疗负担的影响因素分析[J].皮肤性病诊疗学杂志,2025,32(4):263-269,7.基金项目
广东省医学科研基金(B202016) （B202016）
