皮肤性病诊疗学杂志2025，Vol.32Issue(4)：297-305,9.DOI:10.3969/j.issn.1674-8468.2025.04.011
银屑病与代谢共病的系统分析及分子机制探索
Systematic analysis and exploration of molecular mechanisms of psoriasis and metabolic comorbidities
李思佳 1曹哲嘉 1郑思齐 1程淑琼 1钟美珍 1郑跃 1黄晓雯1
作者信息
- 1. 南方医科大学南方医院,广东 广州 510515
- 折叠
摘要
Abstract
Psoriasis is strongly associated with metabolic disorders.Effective management of metabolic dysfunction and individualized treatment strategies for different comorbidities are crucial for preventing disease progression and improving the overall health of psoriatic patients.However,biomarkers that reliably reflecting metabolic status and comorbid metabolic diseases in psoriasis re-main limited.The bidirectional relationship between psoriasis and metabolic disorders stems pri-marily from shared pathophysiological mechanisms,which may mutually activate disease pathways and exacerbate inflammation.This review summarizes the metabolic comorbidities associated with psoriasis and explores potential biomarkers and molecular mechanisms in depth.The goal is to pro-vide new insights for the diagnosis,risk assessment,and personalized treatment of metabolic com-plications in psoriatic patients.关键词
银屑病/代谢紊乱/生物标志物/发病机制Key words
psoriasis/metabolic disorders/biomarkers/pathogenesis引用本文复制引用
李思佳,曹哲嘉,郑思齐,程淑琼,钟美珍,郑跃,黄晓雯..银屑病与代谢共病的系统分析及分子机制探索[J].皮肤性病诊疗学杂志,2025,32(4):297-305,9.
