上海交通大学学报（医学版）2025，Vol.45Issue(4)：452-458,7.DOI:10.3969/j.issn.1674-8115.2025.04.007
老年营养风险指数对住院老年2型糖尿病患者发生肺部感染的预测价值
Predictive value of geriatric nutritional risk index for pulmonary infections in hospitalized elderly patients with type 2 diabetes mellitus
摘要
Abstract
Objective·To investigate the predictive value of the geriatric nutritional risk index(GNRI)for the occurrence of lung infection in hospitalized elderly patients with type 2 diabetes mellitus(T2DM).Methods·Elderly T2DM patients who were admitted to the Geriatric Department of Shanghai Tongren Hospital between June 2022 and June 2024 were retrospectively and consecutively enrolled.They were divided into infected and non-infected groups according to whether lung infection occurred during hospitalization.Baseline data(gender,age,height,weight,duration of diabetes,comorbidities,etc.)were collected and GNRI was calculated.A multivariate Logistic regression model was used to screen the independent risk factors for pulmonary infections,and the predictive value of GNRI for pulmonary infections in T2DM patients was analysed using receiver operating characteristic(ROC)curves.Results·A total of 264 elderly T2DM patients were enrolled,among whom 154 developed pulmonary infections.Significant differences were observed between the infected and non-infected groups in GNRI,albumin,leukocyte count,neutrophil ratio,lymphocyte ratio,glycated hemoglobin,fasting glucose,interleukin-6,C-reactive protein,and procalcitonin levels(P<0.05).Multivariate Logistic regression analysis showed that a lower GNRI was an independent risk factor for lung infection(OR=0.798,95%CI 0.712‒0.894;P<0.001).Correlation analysis showed that GNRI was negatively correlated with C-reactive protein and calcitoninogen.ROC curve analysis showed that GNRI predicted pulmonary infection with an area under the curve of 0.828,a sensitivity of 77.9%,and a specificity of 76.6%.Conclusion·A lower GNRI is an independent risk factor for pulmonary infections in elderly T2DM patients,and also has a good predictive value for the occurrence of pulmonary infections.关键词
老年营养风险指数/2型糖尿病/肺部感染/预测价值Key words
geriatric nutritional risk index(GNRI)/type 2 diabetes mellitus(T2DM)/lung infection/predictive value分类
医药卫生引用本文复制引用
连明珠,张常晓,盛凯,郭梦,方姝予..老年营养风险指数对住院老年2型糖尿病患者发生肺部感染的预测价值[J].上海交通大学学报（医学版）,2025,45(4):452-458,7.基金项目
上海市同仁医院院级科研基金(TRYJ2021LC10). Research Fund of Shanghai Tongren Hospital,Shanghai Jiao Tong University,School of Medicine(TRYJ2021LC10). （TRYJ2021LC10）
