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中缝背核与神经精神疾病关系的研究进展

傅波利 洪浩

药学研究2025,Vol.44Issue(4):364-370,7.
药学研究2025,Vol.44Issue(4):364-370,7.DOI:10.13506/j.cnki.jpr.2025.04.010

中缝背核与神经精神疾病关系的研究进展

Research progress on relationship between dorsal raphe nucleus and neuropsychiatric diseases

傅波利 1洪浩1

作者信息

  • 1. 中国药科大学药学院,江苏南京 211198
  • 折叠

摘要

Abstract

The dorsal raphe nucleus(DRN)is located ventral to the aqueduct of the midbrain,with numerous cell types,complex neural circuits,and a wide range of functions.In recent years,studies have found that DRN may be involved in the regulation of neuropsychiatric processes such as sleep-wakefulness,anxiety,depression,and addiction.This article re-viewed the role and molecular mechanism of DRN-related neural circuits in different neuropsychiatric diseases,in order to provide new ideas for subsequent treatment.

关键词

中缝背核/神经精神疾病/神经环路/分子机制

Key words

Dorsal raphe nucleus/Neuropsychiatric disorders/Neural circuits/Molecular mechanisms

分类

临床医学

引用本文复制引用

傅波利,洪浩..中缝背核与神经精神疾病关系的研究进展[J].药学研究,2025,44(4):364-370,7.

基金项目

国家自然科学基金面上项目(No.82173805) (No.82173805)

科技创新2030"脑科学与类脑研究"重大专项(No.2021ZD0203400) (No.2021ZD0203400)

药学研究

2095-5375

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