药学研究2025,Vol.44Issue(4):364-370,7.DOI:10.13506/j.cnki.jpr.2025.04.010
中缝背核与神经精神疾病关系的研究进展
Research progress on relationship between dorsal raphe nucleus and neuropsychiatric diseases
摘要
Abstract
The dorsal raphe nucleus(DRN)is located ventral to the aqueduct of the midbrain,with numerous cell types,complex neural circuits,and a wide range of functions.In recent years,studies have found that DRN may be involved in the regulation of neuropsychiatric processes such as sleep-wakefulness,anxiety,depression,and addiction.This article re-viewed the role and molecular mechanism of DRN-related neural circuits in different neuropsychiatric diseases,in order to provide new ideas for subsequent treatment.关键词
中缝背核/神经精神疾病/神经环路/分子机制Key words
Dorsal raphe nucleus/Neuropsychiatric disorders/Neural circuits/Molecular mechanisms分类
临床医学引用本文复制引用
傅波利,洪浩..中缝背核与神经精神疾病关系的研究进展[J].药学研究,2025,44(4):364-370,7.基金项目
国家自然科学基金面上项目(No.82173805) (No.82173805)
科技创新2030"脑科学与类脑研究"重大专项(No.2021ZD0203400) (No.2021ZD0203400)