实用医学杂志2025，Vol.41Issue(8)：1105-1110,6.DOI:10.3969/j.issn.1006-5725.2025.08.003
健侧高频重复经颅磁刺激联合生物反馈下的空吞咽训练在脑卒中后吞咽障碍患者中的应用
Application of ipsilateral high-frequency rTMS combined with biofeedback-based air swallowing training in patients with post-stroke dysphagia
摘要
Abstract
Objective To investigate the impact of high-frequency repetitive transcranial magnetic stimula-tion(rTMS)combined with biofeedback-assisted dry swallowing training on treating dysphagia following a stroke.Methods A total of 152 patients with dysphagia after stroke,admitted to the hospital from January 2022 to January 2024,were randomly divided into four groups using a random number table,with 38 cases in each group.The biofeedback group received biofeedback-assisted dry swallowing training,the magnetic stimulation group received high-frequency rTMS on the unaffected side,the combined group received both biofeedback-assisted dry swallowing training and high-frequency rTMS on the unaffected side,and the placebo group received conventional swallowing training and sham rTMS.All interventions lasted for 4 weeks.Clinical efficacy was recorded,and pre-and post-treatment assessments of the upper esophageal sphincter(UES)opening time,opening degree,and pharyngeal contraction duration were performed using multifunctional esophageal manometry.Additionally,swallowing func-tion,nutritional status,neurological function,and quality of life were compared.Results The clinical efficacy of the combined group was higher than that of the biofeedback and magnetic stimulation groups.Post-treatment UES opening time,opening degree,and pharyngeal contraction duration were(205.33±29.01)ms,(1.14±0.34)cm,and(559.19±63.48)ms,respectively,which were significantly better than those in the other 3 groups(P<0.05).The swallowing function scores of the combined group were(6.04±0.83)and(20.03±3.26)points,and significant improvements were observed in swallowing function,nutritional status,neurological function,and quality of life(P<0.05).Conclusion High-frequency rTMS combined with biofeedback-based dry swallowing training signifi-cantly improves the efficacy in the treatment of dysphagia after stroke.关键词
高频重复经颅磁刺激/生物反馈/空吞咽训练/脑卒中/吞咽障碍Key words
high-frequency repetitive transcranial magnetic stimulation/biofeedback/air swallowing training/stroke/dysphagia分类
临床医学引用本文复制引用
高盼盼,张倩,刘婷慧,孙洁..健侧高频重复经颅磁刺激联合生物反馈下的空吞咽训练在脑卒中后吞咽障碍患者中的应用[J].实用医学杂志,2025,41(8):1105-1110,6.基金项目
江苏省自然科学基金面上项目(编号:BK20211088) （编号:BK20211088）
