现代妇产科进展2025，Vol.34Issue(4)：269-273,5.DOI:10.13283/j.cnki.xdfckjz.2025.04.004
转移性卵巢肿瘤的临床分析及文献回顾
Clinical analysis and literature review of secondary tumors of the ovary
杨玲玲 1万冬梅 2王美 3李萌 2李拟东 2王广涵 2梁华茂2
作者信息
- 1. 北京大学第三医院妇产科,国家妇产疾病临床医学研究中心,北京 100191||厦门大学附属妇女儿童医院妇科,厦门 361000
- 2. 北京大学第三医院妇产科,国家妇产疾病临床医学研究中心,北京 100191
- 3. 北京大学第三医院妇产科,国家妇产疾病临床医学研究中心,北京 100191||北京中医医院顺义医院妇产科,北京 101300
- 折叠
摘要
Abstract
Objective:To analyze the clinical characteristics and treatment of secondary tumors of the ovary(STOs).Methods:The clinical and pathological data of patients with STOs admitted in the Department of Gynecology of Peking University Third Hospital from January 1,2000 to September 31,2024 were retrospectively analyzed.Results:A total of 89 patients aged 19～84(50.1±15.4)years were included.The main clinical manifestations were abdominal pain(30 cases),abdominal distension(44 cases),and ascites(37 cases).The primary tumors included 80 cases(89.9%)of non-reproductive system origin and 9 cases(10.1%)of repro-ductive tract origin.The main non-reproductive sources were digestive tract(64/80,80.0%),including gastric cancer,colorectal cancer,appendix cancer,gastrointestinal malignance(not classified),biliary pancreatic cancer,etc.Other non-gynecological sources included breast cancer,unknown primary source,peritoneal pseudomyxoma,etc.STOs of reproductive tract ori-gin included 7 cases of endometrial cancer and 2 cases of cervical cancer.16 patients had once suffered from cancers(5 gastric cancer,4 breast cancer,4 colon cancer,2 endometrial cancer,and 1 appendix cancer),and the median time from the surgery of primary cancer to the discov-ery of ovarian metastases was 3.6(0.5,20.2)years.In the auxiliary examination,the sensitivi-ty of diagnosing STOs was 36.8%(21/57)with CT,26.9%(14/52)with MRI,58.0%(18/31)with positron emission computed tomography(PET-CT),and the difference was statistically significant(P=0.018).The sensitivity of diagnosing digestive tract origin STOs was 74.2%(23/31)with gastroenteroscopy and 27.5%(11/40)with fecal occult blood test,and the difference was statistically significant(P＜0.001).CEA was found to be of diagnostic signifi-cance in identifying digestive tract origin STOs(P=0.031).Twenty-four patients(27.0%)were diagnosed with STOs before operation and transferred to corresponding departments for treatment.Sixty-five patients(73.0%)received gynecological surgery,including 21.5%(14/65)with debulking surgery for ovarian cancer.The accuracy of intraoperative frozen section pa-thology was 47.7%.Conclusion:It is necessary to strengthen the preoperative identification of metastatic ovarian tumors.PET-CT and gastroenteroscopy are helpful to reduce misdiagnosis rate.关键词
转移性/卵巢肿瘤/诊断/治疗Key words
Metastatic/Ovarian tumor/Diagnosis/Treatment分类
医药卫生引用本文复制引用
杨玲玲,万冬梅,王美,李萌,李拟东,王广涵,梁华茂..转移性卵巢肿瘤的临床分析及文献回顾[J].现代妇产科进展,2025,34(4):269-273,5.
