现代医药卫生2025，Vol.41Issue(4)：984-988,5.DOI:10.3969/j.issn.1009-5519.2025.04.035
S100A8/A9在炎症中的作用及机制
The role and mechanism of S100A8/A9 in inflammation
摘要
Abstract
S100A8 and S100A9 belong to the S100 family of calcium-binding protein,which are primari-ly expressed in granulocytes and monocytes.In recent years,studies have found that S100A8/A9 plays a key role in the inflammatory process.S100A8/A9 has been proven to play an important role in various inflamma-tory-related diseases,including infectious inflammation,metabolic inflammation,immune diseases,and degen-erative diseases.Therefore,in-depth research on the role and mechanisms of S100A8/A9 in inflammatory dis-eases is of great significance for revealing the occurrence and development process of diseases,developing new diagnostic tools,and therapeutic strategies.This article reviewed the role and mechanisms of S100A8/A9 in in-flammatory-related diseases,aiming to provide new perspectives and ideas for the diagnosis,treatment,and prevention of these diseases.关键词
S100A8/A9/钙卫蛋白/炎症/作用机制/综述Key words
S100A8/A9/Calprotectin/Inflammation/Mechanism of action/Review分类
基础医学引用本文复制引用
马紫微,曾璐,何旻蕙,邹先琼..S100A8/A9在炎症中的作用及机制[J].现代医药卫生,2025,41(4):984-988,5.基金项目
国家自然科学基金项目(82160185) （82160185）
广西自然科学基金项目(2020GXNSFDA238026). （2020GXNSFDA238026）
