畜牧兽医学报2025，Vol.56Issue(4)：1791-1801,11.DOI:10.11843/j.issn.0366-6964.2025.04.027
岔路黑猪断奶前后粪便菌群和病毒组变化及其相关性研究
Changes of Rectum Microbiota and Virome before and after Weaning and Their Interactions of Chalu Black Pigs
摘要
Abstract
The study aims to explore the change of rectum bacteria and virome before and after weaning and their interactions of Chalu black piglets through 16S rDNA and meta-virome sequen-cing.Feces were collected from the rectal of Chalu black pigs on day 7 before weaning and day 7 after weaning respectively.16S rDNA and meta-virome sequencing were used to analyze the rec-tum microbes change of weaned piglets during the weaning transition.The results showed that,the α diversity of rectum microbiota was increased post-weaning and the β diversity analysis indi-cated a significant change in community structure(P＜0.05).What's more,the relative abun-dance of Firmicutes(P＜0.05),Lactobacillus(P＜0.01)and Limosilactobacillus(P＜0.01)were increased significantly,while the relative abundance of Bacteroidetes(P＜0.05)decreased significatly compared with that of pre-weaning;Meta-virome sequencing illustrated that there was no significant change in α diversity of the virus before and after weaning,but the virome structure changed significantly(P＜0.05).Especially,the relative abundance of Caudoviricetes and Microviridae are having a significant increase after weaning(P＜0.05);Moreover,the intestinal phages interacted with specific bacterial communities,and there was a significant positive correlation be-tween the Akkermansiaceae and Caudovirales family phages(P＜0.05).In summary,the study demon-strated that the effects of weaning stress on the rectum microbiota and virome of piglets and provide new insights into the interactions between rectum microbiota and virome in local pig species,which is benifi-cial in promoting the protection and utilization of local pig breeds in China.关键词
岔路黑猪/断奶应激/病毒组/微生物组Key words
Chalu black pig/weaning stress/virome/microbiome分类
农业科技引用本文复制引用
李苏陈,陆婷婷,陈军光,缪晖,毛海光,韩新燕..岔路黑猪断奶前后粪便菌群和病毒组变化及其相关性研究[J].畜牧兽医学报,2025,56(4):1791-1801,11.基金项目
国家自然科学基金项目(32172765) （32172765）
