摘要
Abstract
Objective To understand the prevalence and epidemiological characteristics of EB virus infection in hospitalized children,and to provide a scientific basis for clinical diagnosis and treatment of EB virus infection.Methods A total of 9960 children who were hospitalized in Affiliated Renhe Hospital of China Three Gorges University from January 2018 to December 2023 were selected as the research objects.ELISA was used to detect EB virus serological antibodies,and the EB virus infection,disease spectrum,clinical symptoms and signs were analyzed.Results Among the 9960 blood samples,7083(71.11%)samples of the antibody profiles indicated EB virus infection,including 971(9.75%)samples were current infections,1305(13.10%)samples were subacute infections,and 4807(48.26%)samples were previous infections.There were 3323 positive cases in 4720 male specimens and 3760 positive cases in 5240 female specimens.The positive rates of male and female were 70.40%and 71.76%,respectively.The highest positive rate of EB virus in the infected age group was 3-6 years old.Among 3150 blood samples,2763 cases of EB virus positive were detected,with a positive rate of 87.71%.In the disease spectrum of 971 children with current infection,there were 357 patients with infectious mononucleosis,accounting for 36.77%;followed by 244 cases of acute bronchitis,accounting for 25.13%;among the constituent ratio of clinical symptoms and signs,children with fever were the most(505 cases),accounting for 52.01%;followed by children with cough and expectoration(215 cases),accounting for 22.14%.Conclusion The infection rate of EB virus in hospitalized children is high,and the positive detection rate of EB virus has age difference.The current infection is mainly in children with infectious mononucleosis.The clinical symptoms and signs are more common in fever.The hospital should formulate corresponding preventive measures according to the characteristics of epidemiology.关键词
EB病毒/住院患儿/流行病学Key words
EB virus/Hospitalized children/Epidemiology分类
医药卫生