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卵巢颗粒细胞自噬研究进展

王莹 张姣姣 王鲜忠 权富生

畜牧兽医学报2025,Vol.56Issue(4):1508-1517,10.
畜牧兽医学报2025,Vol.56Issue(4):1508-1517,10.DOI:10.11843/j.issn.0366-6964.2025.04.004

卵巢颗粒细胞自噬研究进展

Advances in Autophagy of Ovarian Granulosa Cells

王莹 1张姣姣 1王鲜忠 1权富生2

作者信息

  • 1. 西南大学动物医学院,重庆市牧草与草食家畜重点实验室,重庆 400715
  • 2. 西北农林科技大学动物医学院,农业农村部动物生物技术重点实验室,家畜生物学国家重点实验室,杨凌 712100
  • 折叠

摘要

Abstract

Ovarian granulosa cells(GCs)are the basic guarantee of follicle development in female animals.In the past,it was widely believed that apoptosis of GCs could regulate follicle develop-ment.However,recent studies have found that GCs autophagy can also regulate follicle develop-ment.In the animal husbandry industry,the quality of follicle development is closely related to the reproductive rate of female animals,which directly affects the economic benefits of livestock farms.At present,more and more studies have shown that miRNAs are one of the factors regu-lating autophagy in GCs.Therefore,this article will review the research progress on the origin,structure and function of GCs,the importance of GCs autophagy on the ovary,the miRNAs asso-ciated with GCs autophagy of the ovary and their regulatory effects on follicle development,in or-der to provide references for future related studies.

关键词

卵巢颗粒细胞/家畜/细胞自噬/miRNAs

Key words

ovarian granulosa cells/domestic animals/autophagy/miRNAs

分类

农业科技

引用本文复制引用

王莹,张姣姣,王鲜忠,权富生..卵巢颗粒细胞自噬研究进展[J].畜牧兽医学报,2025,56(4):1508-1517,10.

基金项目

西南大学中央高校基本科研业务费(SWU-KQ24020) (SWU-KQ24020)

畜牧兽医学报

OA北大核心

0366-6964

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