现代医药卫生2025，Vol.41Issue(4)：865-869,5.DOI:10.3969/j.issn.1009-5519.2025.04.010
2021-2022年南宁市某妇幼医院儿童呼吸道合胞病毒感染的临床特征及相关因素分析
Analysis of clinical characteristics and related factors of respiratory syncytial virus infection in children at a Maternal and Child Health Hospital in Nanning from 2021 to 2022
摘要
Abstract
Objective To analyze the clinical features and related factors of respiratory syncytial virus(RSV)infection in children.Methods A total of 206 children hospitalized with acute lower respiratory tract infection(ALRTI)in our hospital from June 2021 to June 2022 were collected through the hospital informa-tion system.All children underwent etiological examination,and were divided into the case group and the con-trol group according to whether RSV infection occured.The clinical features of ALRTI children were statisti-cally analyzed,and factors affecting RSV infection in ALRTI children were evaluated using multivariate logis-tic regression.A prediction model was constructed,and the predictive effect of the model for RSV infection in ALRTI children was analyzed using receiver operating characteristic(ROC)curve analysis.Results Among the 206 ALRTI children,51 were positive for RSV antigen or nucleic acid(case group),and 155 were negative(control group).The main symptoms of RSV infected children were cough(96.08％,48/51),fever(64.71％,33/51),shortness of breath/wheezing(23.53％,12/51),and diarrhea/vomiting/chest pain(7.84％,4/51).Sig-nificant differences were found between the two groups in respiratory rate,heart rate,hospitalization time,nu-tritional status,and neutrophil count(P＜0.05).Multivariate logistic regression analysis revealed that respira-tory rate,heart rate,and nutritional status were independent influencing factors for RSV infection in ALRTI children(P＜0.05).The logistic regression prediction model was as follows:ln[1/(1-P)]=5.044+0.025 × respiratory rate+0.016 × heart rate+0.567 × nutritional status.The Hosmer-Lemeshow test showed good goodness-of-fit(x2=3.288,P=0.915).ROC analysis showed an area under the curve(AUC)of 0.745(95％CI 0.663-0.827),with sensitivity and specificity of 74.50％and 69.03％,respectively.Conclusion The clin-ical features of children with RSV infection are primarily cough,fever,and shortness of breath/wheezing.Re-spiratory rate,heart rate,and nutritional status are independent factors affecting RSV infection in ALRTI chil-dren.The prediction model developed shows good predictive value for RSV infection in ALRTI children.关键词
急性下呼吸道感染/呼吸道合胞病毒感染/临床特征/相关因素Key words
Acute lower respiratory tract infection/Respiratory syncytial virus infection/Clinical features/Correlation factor分类
医药卫生引用本文复制引用
陈春秀,黄树稳,颜云盈..2021-2022年南宁市某妇幼医院儿童呼吸道合胞病毒感染的临床特征及相关因素分析[J].现代医药卫生,2025,41(4):865-869,5.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20211403). （Z20211403）
