摘要
Abstract
Objective To analyze the effect of cholecystectomy on gastrointestinal function and prognosis in patients with gallstones.Methods A total of 61 patients with gallstones diagnosed and treated in our hospital from August 2022 to August 2023 were selected as the research objects.They were divided into control group(n=30)and observation group(n=31)by random number table method.The control group was treated with conventional open cholecystectomy,and the observation group was treated with laparoscopic cholecystectomy.The clinical operation indexes,gastrointestinal function indexes[motilin(MTL),gastrin(GAS)],stress response indexes[endothelin(ET),cortisol(Cor),superoxide dismutase(SOD)],complication rate and recurrence rate were compared between the two groups.Results Compared with the control group,the operation time,first exhaust time and hospitalization time of the observation group were shorter,and the intraoperative blood loss was less(P＜0.05).After surgery,the levels of MTL and GAS in the two groups were lower than those before surgery,but compare with the control group,the levels of MTL and GAS in the observation group were higher(P＜0.05).Compared with the control group,ET and Cor in the observation group were lower,and SOD was higher after surgery(P＜0.05).Compared with 16.67%of the control group,the incidence of complications in the observation group was lower(6.45%)(P＜0.05).After 5 months of follow-up,there was no significant difference in the recurrence rate between the observation group and the control group(P＞0.05).Conclusion Cholecystectomy can shorten the operation time,postoperative first exhaust time,hospitalization time,reduce intraoperative blood loss,reduce stress response,and has little effect on gastrointestinal function.In addition,it can achieve the same prognosis as laparotomy,which is worthy of clinical application.关键词
胆囊切除术/胆囊结石/胃肠功能Key words
Cholecystectomy/Gallstones/Gastrointestinal function分类
医药卫生
