摘要
Abstract
Objective To analyze the clinical efficacy of nifedipine in the treatment of pregnancy-induced hypertension(PIH).Methods A total of 76 patients with PIH admitted to the Xinjian District People's Hospital from January 2022 to December 2023 were randomly divided into observation group(38 patients)and control group(38 patients).The control group was treated with magnesium sulfate,and the observation group was treated with nifedipine on the basis of magnesium sulfate.The medication effect,blood pressure index[systolic blood pressure(SBP),diastolic blood pressure(DBP)],symptoms and signs(urinary protein content,edema score),adverse drug reactions and pregnancy outcome were compared between the two groups.Results The treatment efficacy in the observation group was significantly higher than that in the control group(P＜0.05).After treatment,both the SBP and DBP of the two groups were lower than those before treatment,moreover,the SBP and DBP of the observation group were significantly lower than those of the control group(P＜0.05).After treatment,the urine protein content and edema scores of both groups decreased than those before treatment,and those of the observation group were significantly lower than those of the control group(P＜0.05).The incidence of adverse drug reactions was no significant difference between the two groups(P＞0.05).The incidence of adverse pregnancy outcomes in the observation group was significantly lower than that in the control group(P＜0.05).Conclusion Nifedipine is effective in the treatment of PIH,which can alleviate the blood pressure level and clinical symptoms of patients,reduce the risk of adverse pregnancy outcomes,and has high safety.关键词
妊娠高血压综合征/硝苯地平/妊娠结局/尿蛋白/水肿/药物不良反应Key words
Pregnancy-induced hypertension syndrome/Nifedipine/Pregnancy outcome/Urinary protein/Edema/Adverse drug reactions分类
医药卫生
