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尤瑞克林治疗脑梗死的效果及对血清学炎症因子、神经功能恢复、生活质量的影响

周卫凤

医学信息2025,Vol.38Issue(9):129-132,4.
医学信息2025,Vol.38Issue(9):129-132,4.DOI:10.3969/j.issn.1006-1959.2025.09.026

尤瑞克林治疗脑梗死的效果及对血清学炎症因子、神经功能恢复、生活质量的影响

Effect of Urinary Kallidinogenase in the Treatment of Cerebral Infarction and its Influence on Serological Inflammatory Factors,Neurological Function Recovery and Quality of Life

周卫凤1

作者信息

  • 1. 上饶市广丰区人民医院药剂科,江西 上饶 334600
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摘要

Abstract

Objective To evaluate the clinical effect of urinary kallidinogenase in the treatment of cerebral infarction and its effect on serum inflammatory factors,neurological function recovery and quality of life.Methods A total of 60 patients with cerebral infarction admitted to Shangrao Guangfeng District People's Hospital from January 2020 to December 2023 were selected as the research objects,and they were divided into control group and study group according to the random number table method,with 30 patients in each group.The control group was treated with routine treatment,and the study group was treated with urinary kallidinogenase on the basis of routine treatment.The clinical efficacy,serum inflammatory factors[serum C-reactive protein(CRP),interleukin-6(IL-6)]levels,neurological function(NIHSS score,CSS score),quality of life(physical function,physiological function,social function,emotional function)were compared between the two groups.Results Compared with 73.33%of the total effective rate of the control group,the total effective rate of the study group was higher,which was 96.67%(P<0.05).The levels of serum inflammatory factors(CRP,IL-6)in the two groups after treatment were lower than those before treatment,and compared with the control group,the levels of serum inflammatory factors(CRP,IL-6)in the study group after treatment were lower(P<0.05).The NIHSS score and CSS score of the two groups after treatment were lower than those before treatment,the scores of physical function,physiological function,social function and emotional function were higher than those before treatment,and compared with the control group,the NIHSS score and CSS score of the study group after treatment were lower,and the scores of physical function,physiological function,social function and emotional function were higher(P<0.05).Conclusion Urinary kallidinogenase can improve the clinical efficacy of patients with cerebral infarction,improve the inflammatory response,improve the quality of life and neurological function of patients,which is worthy of clinical application.

关键词

尤瑞克林/脑梗死/神经功能

Key words

Urinary kallidinogenase/Cerebral infarction/Neurological function

分类

医药卫生

引用本文复制引用

周卫凤..尤瑞克林治疗脑梗死的效果及对血清学炎症因子、神经功能恢复、生活质量的影响[J].医学信息,2025,38(9):129-132,4.

医学信息

1006-1959

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