摘要
Abstract
Objective To understand the vitamin levels of pregnant women in this hospital,evaluate their nutritional status during pregnancy,and provide basis for guiding pregnant women to rational diet and vi-tamin supplement programs during pregnancy and related disease prevention and control measures.Methods A total of 1 728 pregnant women who underwent routine prenatal check ups at the maternity health clinic of the hospital from January to June 2023 were selected as the research subjects.The age of pregnant women ranges from 18 to 45 years old,with an average of(27.30±4.72)years.Pregnancy weeks range from 5 to 35 weeks,with an average of(15.21±7.40)weeks.The levels of vitamin(Vit)A,E,K and 25-hydroxyvita-min D in serum were quantitatively determined by HPLC tandem mass spectrometry,and the data were statis-tically processed by SPSS20.0 software.Results The serum Vit A level of 1 728 pregnant women was(409.22±102.56)ng/mL,with a deficiency rate of 19.16％(331/1 728).The Vit E level was(9.81±3.03)μg/mL,with a deficiency rate of 1.62％(28/1 728).The level of Vit K was(0.86±0.85)ng/mL,with a defi-ciency rate of 8.22％(142/1 728).The level of 25-hydroxyvitamin D was(22.50±8.11)ng/mL,with a defi-ciency rate of 41.20％(712/1 728).There was no statistically significant difference in serum Vit A,E,and K levels among pregnant women of different age groups(P＞0.05),while the 25-hydroxyvitamin D levels in the elderly group were higher than those in the age appropriate group,and the difference was statistically signifi-cant(P＜0.05).Comparison of serum Vit A,E,K,and 25-hydroxyvitamin D levels in different pregnancy peri-ods revealed that the Vit A levels in late pregnancy was lower than that in the first trimester and the second trimester(P＜0.05),the levels of vitamin K and 25-hydroxyvitamin D in the first trimester were lower than those in the second and late pregnancy,and the differences were statistically significant(P＜0.05).There was no significant difference in Vit E in different pregnancies(P＞0.05).Further analysis showed that the level of Vit E at＞12 to 20 weeks of pregnancy[(10.06±2.56)μg/mL]was relatively low.Conclusion The levels of serum Vit A,E,K and 25-hydroxyvitamin D in pregnant women are deficient in varying degrees.关键词
孕妇/维生素A/维生素E/维生素K/25-羟基维生素DKey words
Pregnant women/Vitamin A/Vitamin E/Vitamin K/25-hydroxyvitamin D分类
医药卫生
