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超声检测胎儿颈项透明层厚度联合血清孕酮及促甲状腺素检测对胎儿产前诊断和妊娠结局的预测价值

谢小英 邓子强 刘志红

医学信息2025,Vol.38Issue(9):158-161,4.
医学信息2025,Vol.38Issue(9):158-161,4.DOI:10.3969/j.issn.1006-1959.2025.09.033

超声检测胎儿颈项透明层厚度联合血清孕酮及促甲状腺素检测对胎儿产前诊断和妊娠结局的预测价值

Predictive Value of Ultrasound Detection of Fetal Nuchal Translucency Thickness Combined with Serum Progesterone and Thyrotropin Detection for Fetal Prenatal Diagnosis and Pregnancy Outcome

谢小英 1邓子强 2刘志红1

作者信息

  • 1. 兴国县中医院产科,江西 兴国 342400
  • 2. 兴国县中医院功能科,江西 兴国 342400
  • 折叠

摘要

Abstract

Objective To investigate the predictive value of ultrasound detection of fetal nuchal translucency thickness(NT)combined with serum progesterone(PROG)and thyrotropin(TSH)in prenatal diagnosis and pregnancy outcome.Methods A total of 62 pregnant women with fetal chromosomal abnormalities in early pregnancy admitted to Xingguo County Hospital of Traditional Chinese Medicine from January 2022 to December 2023 were selected as the study group,and 62 pregnant women with normal fetal development during the same period were selected as the control group.The serum PROG,TSH levels and NT values of pregnant women in the two groups and pregnant women with different pregnancy outcomes in the study group were compared,and the diagnostic efficacy of NT value,PROG and TSH alone and in combination was analyzed.Results The PROG level of the study group was lower than that of the control group,and the TSH level and NT value were higher than those of the control group(P<0.05).Among the 62 pregnant women in the study group,41 had good pregnancy outcomes and 21 had adverse pregnancy outcomes.The PROG level of pregnant women with poor pregnancy outcome was lower than that of pregnant women with good pregnancy outcome,and the TSH level and NT value were higher than those of pregnant women with good pregnancy outcome(P<0.05).The sensitivity of NT value,PROG and TSH combined to predict pregnancy outcome was higher than that of NT value,PROG and TSH alone(P<0.05).Conclusion Ultrasound detection of fetal nuchal translucency thickness combined with serum progesterone and thyrotropin detection is of great value in prenatal diagnosis and pregnancy outcome prediction,which is worthy of clinical application.

关键词

超声检测/胎儿颈项透明层厚度/血清孕酮/促甲状腺素/产前诊断/妊娠结局

Key words

Ultrasonic detection/Fetal nuchal translucency thickness/Serum progesterone/Thyrotropin/Prenatal diagnosis/Pregnancy outcome

分类

医药卫生

引用本文复制引用

谢小英,邓子强,刘志红..超声检测胎儿颈项透明层厚度联合血清孕酮及促甲状腺素检测对胎儿产前诊断和妊娠结局的预测价值[J].医学信息,2025,38(9):158-161,4.

医学信息

1006-1959

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