中国比较医学杂志2025，Vol.35Issue(3)：170-178,9.DOI:10.3969/j.issn.1671-7856.2025.03.015
IV/SPN共感染动物模型的研究进展
Research progress in animal models of influenza virus/Streptococcus pneumoniae co-infection
摘要
Abstract
Bacterial reinfection in the lungs of patients with influenza virus(IV)is a key factor leading to serious illness and death.The adverse consequences caused by co-infection with IV and Streptococcus pneumoniae(SPN)impose a serious burden on patients.However,the specific pathogenesis is complex,how to make better use of the mouse animal model of IV/SPN co-infection for subsequent basic research is of great significance.This article reviews the selection of animals,the selection of pathogen types,the selection of different modeling times,the identification of the co-infection model,and its applications in the IV/SPN co-infection model,so as to provide a reference for the selection of animal models of IV/SPN co-infection in the future.关键词
流感病毒/肺炎链球菌/共感染/动物模型Key words
influenza virus/Streptococcus pneumoniae/co-infection/animal model引用本文复制引用
杨建树,王雪峰,张秀英,穆婧雯,徐文涛..IV/SPN共感染动物模型的研究进展[J].中国比较医学杂志,2025,35(3):170-178,9.基金项目
国家自然科学基金(82374521) （82374521）
国家传承创新中心重点病种项目(2023-247). （2023-247）
