中国现代医学杂志2025，Vol.35Issue(9)：33-39,7.DOI:10.3969/j.issn.1005-8982.2025.09.006
二维斑点追踪超声心动图早期评估冠状动脉狭窄程度的临床价值
Clinical value of two-dimensional speckle tracking echocardiography for early assessment of the degree of coronary stenosis
摘要
Abstract
Objective To investigate the clinical value of two-dimensional speckle tracking echocardiography(2D-STE)in the early assessment of coronary artery stenosis.Methods A total of 100 coronary heart disease(CHD)patients who underwent coronary angiography(CAG)and 2D-STE were enrolled and categorized into mild(Gensini score<25,n=34),moderate(25 to 49,n=24),and severe(≥50,n=35)stenosis groups,with 25 controls showing normal coronary arteries.Differences in global longitudinal strain(GLS),segmental longitudinal strain(LS),peak strain dispersion(LS-PSD),and maximum peak time difference(LS-Dif)were analyzed.Multivariate linear regression identified factors influencing stenosis severity,with receiver operating characteristic(ROC)curves plotted.Results The severe group showed higher GLS than control,mild,and moderate groups(P<0.05);the moderate group exceeded control and mild groups(P<0.05);the mild group surpassed controls(P<0.05).LS-PSD was greater in severe and moderate groups versus control and mild groups(P<0.05),with no significant difference between moderate and severe groups(P>0.05).LS-Dif followed similar trends.GLS and segmental LS were independent risk factors for stenosis severity(P<0.05).For 75～<90%stenosis,segmental LS(cutoff:-14.0%)showed optimal diagnostic performance(AUC=0.819;sensitivity=60.75%;specificity=79.13%).For≥90%stenosis,GLS(cutoff:-12.5%)demonstrated superior efficacy(AUC=0.877;sensitivity=70.97%;specificity=92.86%).Conclusion 2D-STE serves as a safe,noninvasive adjunct to CAG for early coronary stenosis evaluation in CHD patients.关键词
冠状动脉狭窄/二维斑点追踪超声心动图/超声/冠状动脉造影Key words
coronary artery stenosis/two-dimensional speckle tracking echocardiography/ultrasonography/coronary angiography分类
医药卫生引用本文复制引用
李玥霖,张新国,贺琳,潘诗垚..二维斑点追踪超声心动图早期评估冠状动脉狭窄程度的临床价值[J].中国现代医学杂志,2025,35(9):33-39,7.基金项目
湖南省卫生健康委科研计划项目(No:202209023145) （No:202209023145）
