中国真菌学杂志2025，Vol.20Issue(2)：148-152,5.
1990-2024年中国赛多孢霉感染的流行病学回顾性分析
A retrospective analysis of Scedosporium infections in China from 1990 to 2024
摘要
Abstract
Objective To explore the epidemiological characteristics of scedosporiosis from China.Methods The species diversity,infected organ,diagnosis,treatment,and outcome of the reported cases of scedosporiosis from China were retro-spectively reviewed in the past 40 years.Results A total of 90 reported cases of scedosporiosis have been included,in which S.apiospermum/S.boydii and lung(41.1%)were the most common Scedosporium spp.and affected organs,respective-ly.Several infection pathways,such as injury(33.3%),immunosuppression(23.3%),and near-drowning(22.2%)are the most common infection pathways.Up to now,it is still the main diagnostic method to have positive cultures(96.7%),and molecular identification is also increased(86.2%),especially in the past five years.Voriconazole was the leading anti-fungal therapy,and its cure/improvement rate is 76.3%,which was consistent with global guidelines.Conclusions The in-cidence of scedosporiosis has increased steadily in China.Due to the low proportion of molecular techniques used in mycology identification,bias might be appeared in the exploration of incidence of scedosporiosis in China.Notably,voriconazole is rec-ommended as the first-line treatment for Scedosporium infection worldwide.However,it is relatively limited in its use(65.6%)in China.关键词
赛多孢霉感染/赛多孢霉/流行病学/中国Key words
scedosporiosis/Scedosporium/epidemiology/China分类
临床医学引用本文复制引用
韩明原,陈敏..1990-2024年中国赛多孢霉感染的流行病学回顾性分析[J].中国真菌学杂志,2025,20(2):148-152,5.基金项目
国家自然科学基金(82172291) （82172291）
