中国药房2025，Vol.36Issue(9)：1123-1128,6.DOI:10.6039/j.issn.1001-0408.2025.09.18
利用ECHO模型评价药学质控对药物治疗管理服务的影响
Influence evaluation of pharmaceutical quality control on medication therapy management services by the ECHO model
摘要
Abstract
OBJECTIVE To evaluate the influence of pharmaceutical quality control on the efficiency and outcomes of standardized medication therapy management(MTM)services for patients with coronary heart disease by using Economic,Clinical and Humanistic Outcomes(ECHO)model.METHODS This study collected case data of coronary heart disease patients who received MTM services during January-March 2023(pre-quality control implementation group,n=96)and June-August 2023(post-quality control implementation group,n=164).Using propensity score matching analysis,80 patients were selected from each group.The study subsequently compared the economic,clinical,and humanistic outcome indicators of pharmaceutical services between the two matched groups.RESULTS There were no statistically significant differences in baseline data between the two groups after matching(P＞0.05).Compared with pre-quality control implementation group,the daily treatment cost(16.26 yuan vs.24.40 yuan,P＜0.001),cost-effectiveness ratio[23.12 yuan/quality-adjusted life year(QALY)vs.32.32 yuan/QALY,P＜0.001],and the incidence of general adverse drug reactions(2.50%vs.10.00%,P=0.049)of post-quality control implementation group were decreased significantly;the utility value of the EuroQol Five-Dimensional Questionnaire(0.74±0.06 vs.0.71±0.07,P=0.003),the reduction in the number of medication related problems(1.0 vs.0.5,P＜0.001),the medication adherence score[(6.32±0.48)points vs.(6.10±0.37)points,P=0.001],and the satisfaction score[(92.56±1.52)points vs.(91.95±1.56)points,P=0.013]all showed significant improvements.Neither group experienced serious adverse drug reactions.There was no statistically significant difference in the incidence of new adverse reactions between the two groups(1.25%vs.3.75%,P=0.310).CONCLUSIONS Pharmaceutical quality control can improve the quality of pharmaceutical care,and the ECHO model can quantitatively evaluate the effect of MTM services,making pharmaceutical care better priced and more adaptable to social needs,thus being worthy of promotion.关键词
药物治疗管理/药学质控/ECHO模型/药学服务Key words
medication therapy management/pharmaceutical quality control/ECHO model/pharmaceutical care分类
医药卫生引用本文复制引用
刘坤,陈云飞,齐亚娟,戈艳蕾,付爱双,蒋欢欢,李玉双,黄炎,张倩影,陈冬,谷秀林,封锦慧,王紫监..利用ECHO模型评价药学质控对药物治疗管理服务的影响[J].中国药房,2025,36(9):1123-1128,6.基金项目
河北省卫生健康委2020年政府资助临床医学人才培养项目(No.冀卫办科教[2021]1号) （No.冀卫办科教[2021]1号）
