中国中医眼科杂志2025，Vol.35Issue(5)：415-420,6.DOI:10.13444/j.cnki.zgzyykzz.2025.05.003
238例深圳地区过敏性结膜炎患者中医证素分布特点
Clinical Research of Traditional Chinese Medicine Syndrome Elements Distribution and Combination Characteristics in 238 Patients with Allergic Conjunctivtis in Shenzhen
摘要
Abstract
OBJECTIVE To investigate the distribution characteristics of Traditional Chinese Medicine(TCM)syndrome elements in patients with allergic conjunctivitis(AC).METHODS A total of 238 AC patients(476 eyes)from the ophthalmology clinic of Shenzhen Traditional Chinese Medicine Hospital between January 2022 and December 2022 were included.Clinical symptoms,signs,and TCM four-diagnostic data were collected.TCM syndrome scales were completed,and syndrome elements were extracted based on the syndrome differentiation scale using patients'symptoms,signs,tongue and pulse characteristics.Allergy skin prick tests(SPT)were performed.The distributions of TCM syndrome elements,syndrome patterns,and syndrome components were analyzed,along with correlations between age,gender,SPT results,and TCM syndrome patterns.RESULTS(1)Syndrome elements:25 elements were identified,including 11 disease-location elements.The top five were lung(92 times,38.55%),liver(36 times,15.13%),spleen(29 times,12.18%),skin(27 times,11.34%),and stomach(20 times,8.40%).Fourteen disease-nature elements were identified,with the top five being heat(78 times,32.77%),external wind(73 times,30.67%),Yin deficiency(41 times,17.23%),dampness(29 times,12.18%),and blood deficiency(28 times,11.76%).(2)Clinical manifestations:73 symptoms were recorded.The top five were ocular redness(238 times,100%),ocular itching(238 times,100%),excessive eye discharge(211 times,88.66%),blurred vision(208 times,87.39%),and emaciation(198 times,83.19%).(3)Syndrome patterns:32 patterns were identified.The most frequent were wind-heat invading lung syndrome(48 times,20.27%),followed by wind-dampness invading lung syndrome(21 times,8.82%),liver blood deficiency syndrome(20 times,8.40%),half-exterior half-interior syndrome(17 times,7.14%),stomach heat with Yin deficiency syndrome(14 times,5.88%),and lung heat with Yin deficiency syndrome(12 times,5.04%).(4)SPT results:Six cases(+),46(++),90(+++).(5)Correlations:Wind-heat invading lung syndrome(r=0.997,P=0.003),liver blood deficiency syndrome(r=0.991,P=0.009),half-exterior half-interior syndrome(r=0.969,P=0.031),and stomach heat with Yin deficiency syndrome(r=0.956,P=0.044)showed positive correlations with SPT results.Wind-heat invading lung syndrome correlated with disease onset age(r=0.956,P=0.044).Gender differences were observed in half-exterior half-interior syndrome(χ2=4.581,P=0.033;more common in females)and lung heat with Yin deficiency syndrome(χ2=6.389,P=0.012;more common in males).CONCLUSIONS In Shenzhen AC patients,wind-heat invading lung syndrome is predominant.Lung and liver are key syndrome elements.Gender,age,and SPT results influence TCM syndrome differentiation.关键词
过敏性结膜炎/证素/病性/病位/WF文锋-Ⅲ中医(辅助)诊疗系统Key words
allergic conjunctivtis/syndrome elements/location of disease/pathogen of dis-ease/WF wenfeng-Ⅲ TCM(auxiliary)diagnosis and treatment system分类
医药卫生引用本文复制引用
左志琴,辛娜,沈志华..238例深圳地区过敏性结膜炎患者中医证素分布特点[J].中国中医眼科杂志,2025,35(5):415-420,6.基金项目
1国家自然科学基金项目(81503619)2广东省中医药管理局科研项目(2022021) （81503619）
