中国中医眼科杂志2025，Vol.35Issue(5)：421-427,481,8.DOI:10.13444/j.cnki.zgzyykzz.2025.05.004
308例PDR患者中医体质分布情况及相关因素分析
Distribution of Traditional Chinese Medicine Constitution Types and Analysis of Re-lated Factors in 308 Patients with Proliferative Diabetic Retinopathy
摘要
Abstract
OBJECTIVE To preliminary explore the distribution characteristics of Traditional Chinese Medicine(TCM)constitution types in patients with proliferative diabetic retinopathy(PDR),and to provide a research foundation and objective evidence for the individualized prevention and treatment of non-proliferative diabetic retinopathy(NPDR)progressing to PDR using TCM clinically.METHODS The study included patients who were diagnosed with PDR and received outpatient treatment at Tianjin Medical University Eye Hospital from November 2022 to April 2023.The patients were surveyed using the"TCM Constitution Questionnaire".Valid questionnaires were entered into EpiData 3.1 software.The constitution of the subjects was determined based on their questionnaire scores and statistical analysis was conducted.RESULTS(1)General Information:A total of 308 valid questionnaires were collected.Among them,there were 160 males(51.95%)and 148 females(48.05%);The average age was(53.80±11.64)years;The average duration of diabetes was(13.63±8.59)years;And the average fasting blood glucose was(8.13±1.90)mmol/L.(2)Overall distribution of TCM constitution types:There were 74 cases(24.03%)of balanced constitution and 234 cases(75.97%)of unbalanced constitution.There were 64 cases(20.78%)of single unbalanced constitution and 170 cases(55.19%)of two or more unbalanced constitution types.The balanced constitution accounted for the largest proportion,followed by Qi deficiency,damp-heat,Yang deficiency,Yin deficiency,phlegm-dampness,Qi stagnation,blood stagnation,special diathesis,in descending order of frequency.(3)Distribution of TCM constitutional types:There was a statistically significant difference in the distribution of TCM constitutional types among different age groups(χ2=38.710,P=0.001).There was a statistically significant difference in the distribution of TCM constitutional types among patients with different durations of diabetes(χ2=20.340,P=0.009).There was a statistically significant difference in the distribution of TCM constitutional types among patients with different fasting blood glucose levels(χ2=32.500,P=0.008).(4)Relationship between influencing factors of PDR and TCM constitutional types:There was a statistically significant difference in the impact of fasting blood glucose between balanced and unbalanced constitutions(χ²=7.555,P=0.023).However,there were no statistically significant differences in the impact of gender,age group,and duration of diabetes between balanced and unbalanced constitutions(P>0.05).There were no statistically significant differences in the distribution of prognostic factors for PDR between single and combined TCM constitutional types(P>0.05).(5)Correlation analysis among various unbalanced constitutions:The correlation coefficients between the special diathesis and other unbalanced constitutions were relatively low,while there were strong positive correlations between Qi deficiency and Qi stagnation,phlegm-dampness and Qi stagnation,Qi deficiency and phlegm-dampness,and phlegm-dampness and damp-heat,with statistically significant difference(P＜0.05).CONCLUSIONS Qi deficiency,damp-heat,and Yang deficiency are the main unbalanced constitutional types in patients with PDR.Regulating and improving the TCM constitutional types of patients with NPDR from these three perspectives may help prevent or slow the progression of this type of patient to PDR,thereby improving their quality of life.关键词
中医体质/增殖性糖尿病视网膜病变/影响因素/体质兼杂Key words
Traditional Chinese Medicine constitution/proliferative diabetic retinopathy/in-fluencing factors/mixed constitutions分类
医药卫生引用本文复制引用
尚姗姗,程朝晖,温银萍,于国荣,邢东军,李嫦,苏艳,李志清..308例PDR患者中医体质分布情况及相关因素分析[J].中国中医眼科杂志,2025,35(5):421-427,481,8.基金项目
1天津市中医药管理局中医中西医结合科研课题(2021033)2北京中医药大学青年教师项目(2018-JYBZZ-JS179) （2021033）
