中国医院用药评价与分析2025，Vol.25Issue(4)：412-415,4.DOI:10.14009/j.issn.1672-2124.2025.04.007
补肾柔肝祛瘀汤联合电针对薄型子宫内膜患者子宫内膜血流阻力指数、内分泌指标的影响研究
Effects of Bushen Rougan Quyu Decoction Combined with Electroacupuncture on Endometrial Blood Flow Resistance and Endocrine Indicators in Patients with Thin Endometrium
摘要
Abstract
OBJECTIVE:To probe into the therapeutic effects of Bushen Rougan Quyu decoction combined with electroacupuncture in the treatment of patients with thin endometrium.METHODS:A prospective study method was used,a total of 90 patients with endometrium admitted into outpatient department in the hospital from Jan.2023 to Apr.2024 were selected to be divided into group A(given conventional Western medicine),group B(given Bushen Rougan Quyu decoction)and group C(Bushen Rougan Quyu decoction combined with electroacupuncture)via random number table method,with 30 cases in each group.Changes of endometrial thickness,endometrial artery blood flow resistance index and endocrine indicator before and after treatment were observed,the pregnancy rate and incidence of adverse drug reactions were calculated.RESULTS:After treatment,the endometrial thicknesses of the three groups were greater than those before treatment,with statistically significant differences(P<0.05);the differences were statistically significant in the comparison of group B with groups A and group C(P<0.05);and the difference was not statistically significant difference in the comparison of groups A and group C(P>0.05).After treatment,the estradiol and progesterone levels of three groups were higher than those before treatment,with statistically significant differences(P<0.05),while the difference was not statistically significant in the comparison among three groups(P>0.05).After treatment,the endometrial artery blood flow pulsatility indexes(PI)and resistance indexes(RI)of three groups were lower than those before treatment,the PI and RI of groups A and group C were lower than those of group B,with statistically significant differences(P<0.05);the differences were not statistically significant in the comparison of PI and RI between group A and group C(P>0.05).After treatment,the pregnancy rates of group A,group B and group C were 30.00%(9/30),16.67%(5/30)and 46.67%(14/30),respectively;the group B were significantly lower than that of groups A and group C,with statistically significant differences(P<0.05);the group C were slightly higher than that of group A,while the difference was not statistically significant(P>0.05).The incidences of adverse drug reactions of group B and group C were respectively 3.33%(1/30)and 3.33%(1/30),lower than 20.00%(6/30)of group A,with statistically significant differences(P<0.05).CONCLUSIONS:The application of Bushen Rougan Quyu decoction combined with electroacupuncture in the treatment of thin endometrium can help to increase the endometrial thickness,regulate the endocrine level,and further improve the blood supply of endometrium to promote pregnancy,with better safety and effectiveness.关键词
薄型子宫内膜/补肾柔肝祛瘀汤/电针/子宫内膜厚度/血流阻力指数/内分泌指标Key words
Thin endometrium/Bushen Rougan Quyu decoction/Electroacupuncture/Endometrial thickness/Blood flow resistance index/Endocrine indicators分类
药学引用本文复制引用
贾红伟,白杰,赵彦..补肾柔肝祛瘀汤联合电针对薄型子宫内膜患者子宫内膜血流阻力指数、内分泌指标的影响研究[J].中国医院用药评价与分析,2025,25(4):412-415,4.基金项目
河北省中医药管理局科研计划项目(No.2023371) （No.2023371）
