中国医院用药评价与分析2025，Vol.25Issue(4)：438-441,4.DOI:10.14009/j.issn.1672-2124.2025.04.013
喹硫平联合认知行为疗法对精神分裂症患者负性情绪、药物依从性的影响研究
Effects of Quetiapine Combined with Cognitive Behavioral Therapy on Negative Emotions and Medication Compliance in Patients with Schizophrenia
鲁满云 1胡孝芬 1韩友松 1杨映丹1
作者信息
- 1. 安庆市第六人民医院临床心理科,安徽 安庆 246000
- 折叠
摘要
Abstract
OBJECTIVE:To probe into the effects of quetiapine combined with cognitive behavioral therapy on negative emotions and medication compliance in patients with schizophrenia.METHODS:A total of 110 patients with schizophrenia who were treated in the Clinical Psychology Department of the hospital from Jul.2022 to Oct.2023 were selected for a retrospective study,which were divided into control group(53 cases,received quetiapine)and observation group(57 cases,received quetiapine combined with cognitive behavioral therapy)according to different treatment methods recorded in the medical record system,both groups were compared in terms of the State-Trait Anxiety Inventory(STAI),Medication Adherence Scale(MAS),Positive and Negative Symptom Scale(PANSS)and Schizophrenic Quality of Life Scale(SQLS)scores.RESULTS:Before treatment,there were no statistically significant differences in STAI,MAS,PANSS and SQLS scores between two groups(P>0.05).After treatment,the STAI,PANSS and SQLS scores of observation group were lower than those of the control group,and the MAS score was higher than that of the control group,with statistically significant differences(P<0.05).CONCLUSIONS:Quetiapine combined with cognitive-behavioral therapy can improve the clinical symptoms,alleviate anxiety,improve drug compliance and quality of life for patients to a certain extent.关键词
精神分裂症/喹硫平/认知行为疗法/负性情绪/药物依从性Key words
Schizophrenia/Quetiapine/Cognitive behavioral therapy/Negative emotions/Medication compliance分类
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鲁满云,胡孝芬,韩友松,杨映丹..喹硫平联合认知行为疗法对精神分裂症患者负性情绪、药物依从性的影响研究[J].中国医院用药评价与分析,2025,25(4):438-441,4.
