中国中医药信息杂志2025，Vol.32Issue(4)：180-186,7.DOI:10.19879/j.cnki.1005-5304.202403676
瓜子金化学成分和药理作用研究进展及其质量标志物预测分析
Research Progress in the Chemical Composition and Pharmacological Effects of Polygalae Japonicae Herba and Predictive Analysis on Its Quality Markers
摘要
Abstract
Polygalae Japonicae Herba has the functions of expectorant and relieving cough,promoting blood circulation and detumescence,detoxification and relieving pain.It mainly contains triterpene saponins,flavonoids,xanthones,oligosaccharides and other active components,which has many pharmacological effects,such as anti-inflammatory,analgesic,neuroprotective,anti-tumor,regulation of lipid metabolism,anti-infective preterm birth,etc.,and shows good efficacy in in the treatment of nervous,metabolic and other system diseases.This article reviewed the chemical composition and pharmacological effects of Polygalae Japonicae Herba,combining the concept of quality markers of Chinese materia medica,predicted and analyzed the quality markers of Polygalae Japonicae Herba based on plant phylogenetics,uniqueness of chemical components,efficacy of Chinese materia medica,pharmacological properties of Chinese materia medica,new pharmacological effects,detectability of chemical components,network pharmacology and molecular docking technology,in order to provide reference for the study on the material basis of the medicinal effects and quality standards of Polygalae Japonicae Herba.关键词
瓜子金/化学成分/瓜子金皂苷己/药理作用/质量标志物/预测分析Key words
Polygalae Japonicae Herba/chemical composition/polygalasaponin F/pharmacological effects/Q-marker/predictive analysis分类
医药卫生引用本文复制引用
刘明英,王春雷,梁晓东,刘轶凡..瓜子金化学成分和药理作用研究进展及其质量标志物预测分析[J].中国中医药信息杂志,2025,32(4):180-186,7.基金项目
国家自然科学基金青年科学基金(82405291) （82405291）
山东中医药大学青年科研创新团队(2020-54) （2020-54）
山东中医药大学教学名师工作室(2022年) （2022年）
