中国中医药信息杂志2025，Vol.32Issue(4)：187-192,6.DOI:10.19879/j.cnki.1005-5304.202401465
针刺干预抑郁症脑网络机制研究进展
Research Progress in Brain Network Mechanism of Acupuncture Intervention in Depression
摘要
Abstract
Acupuncture is considered both safe and effective for treating depression;however,its underlying mechanism remains incompletely understood.This article reviewed the mechanisms of acupuncture in depression from the perspective of brain network dynamics.It has been found abnormal alterations in the structural and functional brain networks,including the default mode network,cognitive control network,salience network and affective network in individuals with depression.Acupuncture has been shown to enhance the diffusion anisotropy value of white matter and repair the microstructure of white matter fiber bundles in key brain regions.It can also modulate the activation the functional brain networks,either globally or in specific network segments,improve functional connectivity within and between functional networks,regulate global transmission efficiency and connectivity patterns of functional networks,restore brain network interaction balance,regulate abnormal integration of functional networks,and improve emotional regulation ability and cognitive function,in order to alleviate the clinical symptoms of depression and serve as an effective antidepressant therapy,which can provide reference for the study of acupuncture intervention in the brain network mechanism of depression.关键词
针刺/抑郁症/脑网络/结构网络/功能网络/综述Key words
acupuncture/depression/brain network/structural network/functional network/review分类
医药卫生引用本文复制引用
刘斗,张惠春,申亚男,李蜀娟,肖敏,李芃菲,马重兵..针刺干预抑郁症脑网络机制研究进展[J].中国中医药信息杂志,2025,32(4):187-192,6.基金项目
国家自然科学基金(82360974) （82360974）
甘肃省高校青年博士支持项目(2023QB-088) （2023QB-088）
甘肃中医药大学2020-2021年引进人才科研启动基金项目(2023YJRC-01) （2023YJRC-01）
甘肃省针灸推拿临床医学中心开放基金项目(ZJKF2204) （ZJKF2204）
