中国医院用药评价与分析2025，Vol.25Issue(4)：474-478,483,6.DOI:10.14009/j.issn.1672-2124.2025.04.020
2 169张门诊雷公藤制剂处方用药分析及药学监护策略
Drug Use Analysis and Pharmaceutical Care Strategies for 2 169 Outpatient Prescriptions of Tripterygium Wilfordii Preparations
摘要
Abstract
OBJECTIVE:Taking Tripterygium wilfordii glycosides tablets as an example,to explore the application rationality of Tripterygium wilfordii preparations and pharmaceutical care strategies,so as to provide references for the rational application of Tripterygium wilfordii preparations and other high-risk Chinese patent medicines.METHODS:Through the hospital information system,the outpatient prescription information of Tripterygium wilfordii glycosides tablets in Guang'anmen Hospital,China Academy of Chinese Medical Sciences(hereinafter referred to as"the hospital")from Mar.to Dec.2023 was collected and statistically analyzed.Clinical medication monitoring strategies for Tripterygium wilfordii preparations were analyzed.RESULTS:The total number of outpatient prescriptions for Tripterygium wilfordii glycosides tablets in the hospital from Mar.to Dec.2023 was 2 169,with ages ranged from 20 to 93 years.Among them,660 were males and 1 509 were females.The patients were mainly from the Department of Rheumatology(1 602 cases,73.86%),Dermatology(266 cases,12.26%)and Nephropathy Outpatient(178 cases,8.21%).There was a high risk of drug use of Tripterygium wilfordii glycosides tablets in the hospital.The key points of monitoring were drug use for special groups,off-label dosage,off-label course of treatment and off-label indication,the number of off-label indication prescriptions was 38.54%(836 prescriptions).CONCLUSIONS:Tripterygium wilfordii glycosides tablets and other Tripterygium wilfordii preparations are widely used in clinical practice,with a wide age distribution of patients.Pharmaceutical monitoring strategies should be summarized to promote rational drug use in clinic,strengthen medication monitoring,reduce the occurrence of adverse drug reactions,promote rational use of Tripterygium wilfordii preparations,and provide reference for pharmaceutical monitoring and management of other high-risk pharmaceuticals.关键词
雷公藤制剂/临床应用/药学监护/合理用药Key words
Tripterygium wilfordii preparations/Clinical application/Pharmaceutical care/Rational drug use分类
医药卫生引用本文复制引用
周燊,宋新,侯新,陈雯,金敏..2 169张门诊雷公藤制剂处方用药分析及药学监护策略[J].中国医院用药评价与分析,2025,25(4):474-478,483,6.基金项目
北京药学会临床药学研究项目(No.LCYX-2024-12) （No.LCYX-2024-12）
白求恩公益基金会"2022白求恩·求索-药学科研能力建设"项目 （）
中国中医科学院中药监管科学研究项目(No.中科科便函[2024]25号) （No.中科科便函[2024]25号）
