中国中医药信息杂志2025，Vol.32Issue(5)：62-67,6.DOI:10.19879/j.cnki.1005-5304.202404665
国内中医药防治便秘临床试验注册现况分析
Analysis on Current Status of Clinical Trial Registration on TCM Prevention and Treatment of Constipation in China
摘要
Abstract
Objective To investigate the distribution characteristics and future trends of clinical trials related to TCM prevention and treatment of constipation by analyzing the clinical trials registered in the Chinese Clinical Trial Registry(ChiCTR).Methods The clinical trials data related to TCM prevention and treatment of constipation in the ChiCTR database were retrieved from the establishment of the database to April 15,2024.Excel 2019 was utilized for de-duplication.Subsequently,SPSS 26.0 was employed to analyze the general characteristics,research types,intervention measures,etc.of the included trials,charts were drawn,and the clinical trial characteristics were summarized.Results A total of 107 clinical trials were included,with 102 being pre-registered,involving 21 provincial-level administrative regions and 75 clinical institutions.The top five regions in terms of the number of registered clinical trials were Beijing(19.63%),Shanghai(15.89%),Guangdong(14.02%),Sichuan(10.28%)and Jiangsu(9.35%).The top three sources of funding were local finance(28.97%),self-raised funds(18.69%)and hospital-funded funds(15.89%).The research types were mostly intervention studies(92.52%),of which 41 explicitly stated the use of blinding methods,and the main research design type is randomized parallel controlled trial.Conclusion The number of clinical trials related to TCM prevention and treatment of constipation registered in ChiCTR is on an upward trend.However,there is a noticeable geographical imbalance in the distribution of these trials,and there is a need for further improvement in the quality of trial design and the standardization of registration information.关键词
便秘/中医药/临床试验/中国临床试验注册中心Key words
constipation/TCM/clinical trials/Chinese Clinical Trial Registry分类
医药卫生引用本文复制引用
黄硕,梁彪,杨忆衡,倪嘉淳,钱诗维,王振宜..国内中医药防治便秘临床试验注册现况分析[J].中国中医药信息杂志,2025,32(5):62-67,6.基金项目
国家自然科学基金面上项目(82274531、81973859) （82274531、81973859）
上海市卫生健康委员会卫生行业临床研究专项面上项目(202140185) （202140185）
