中国中医药信息杂志2025，Vol.32Issue(5)：187-192,6.DOI:10.19879/j.cnki.1005-5304.202404510
山茱萸及其有效成分防治神经退行性疾病研究进展
Research Progress in Corni Fructus and Its Active Components for the Prevention and Treatment of Neurodegenerative Diseases
摘要
Abstract
Neurodegenerative diseases(NDs)are a series of disorders characterized by varying degrees of cognitive and mobility impairment,with increasing incidence in recent years.Currently,the treatment of these diseases is mainly based on drug therapy,and there are no effective methods for reversing the course of the diseases.Corni Fructus has the efficacy of tonifying the liver and kidney,and astringency and arresting,which is effective to various types of NDs.This article summarized the pharmacological effects of Corni Fructus,including anti-inflammatory,anti-oxidative stress,regulation of mitochondrial function,modulation of autophagy,inhibition of neuronal apoptosis,and epigenetic modulation,and sorted out the research progress of Corni Fructus and its active components in the treatment of NDs,such as Alzheimer disease,Parkinson disease,multiple sclerosis,and so on,with a view to providing a reference for further research and clinical application of Corni Fructus in NDs.关键词
山茱萸/神经退行性疾病/有效成分/作用机制Key words
Corni Fructus/neurodegenerative diseases/active components/mechanism分类
医药卫生引用本文复制引用
姚佳霖,白绿峰,关运祥,钱百成,郜浩帆,王宝亮..山茱萸及其有效成分防治神经退行性疾病研究进展[J].中国中医药信息杂志,2025,32(5):187-192,6.基金项目
国家中医药管理局全国名老中医药专家传承工作室建设项目(2022年) （2022年）
河南省中医药拔尖人才培养项目(2022ZYBJ06) （2022ZYBJ06）
河南省第二批中医药青苗人才培养项目(2021年) （2021年）
