转化医学杂志2025，Vol.14Issue(3)：50-55,6.DOI:10.3639/j.issn.2095-3097.2025.03.011
椎旁肌CT值与骨质疏松性腰椎骨折患者经皮椎体成形术后再骨折的关系
The Relationship between Paravertebral Muscle CT Values and Refractures after Percutaneous Vertebroplasty in Patients with Osteoporotic Lumbar Fractures
摘要
Abstract
Objective To investigate the relationship between paravertebral muscle CT values and re-fracture after percutaneous vertebroplasty(PVP)in patients with osteoporotic lumbar fracture.Methods A total of 120 cases with osteo-porotic lumbar fracture who underwent PVP from April 2022 to April 2023 were selected.All patients received 1-year radio-graphic follow-up.According to the occurrence of osteoporotic vertebral refracture,120 patients were divided into refracture group(n=26)and non-refracture group(n=94).The CT values of paravertebral muscles(mean CT values of posterior vertebral muscles and mean CT values of psoas major muscles)were measured in all subjects.Spearman correlation analysis was used to investigate the relationship between paravertebral muscle CT value and re-fracture after PVP.Receiver operating character-istic(ROC)curve analysis was used to analyze the predictive value of paravertebral muscle CT value on re-fracture after PVP,and multi-factor logistic regression was used to analyze the influencing factors of re-fracture after PVP.Results The average CT values of posterior vertebral muscle group and psoas major muscle in refracture group were lower than those in non-refrac-ture group(P<0.05).The mean CT values of posterior vertebral muscle group and psoas major muscle in patients with osteopo-rotic lumbar fracture were negatively correlated with refractures after PVP(P<0.05).The AUC of posterior vertebral muscle and psoas major muscle were 0.731(95%CI:0.681-0.776)and 0.849(95%CI:0.799-0.894),respectively,and the AUC of com-bined prediction was 0.907(95%CI:0.857-0.952).The age,body mass index,bone cement injection amount and the proportion of bone cement leakage in the re-fracture group were higher than those in the non-re-fracture group,and the bone mineral density T value was lower than that in the non-re-fracture group(P<0.05).Age(OR=1.893,95%CI:1.150-3.114),bone cement leakage(OR=2.067,95%CI:1.249-3.420),bone mineral density(OR=2.649,95%CI:1.626-4.315),bone cement injection volume(OR=2.368,95%CI:1.491-3.761),average CT value of posterior vertebral muscle group(OR=2.821,95%CI:1.658-4.798),average CT value of psoas major muscle(OR=3.267,95%CI:1.944-5.493)were the influencing factors of re-fracture after PVP(P<0.05).Conclusion Paravertebral muscle CT is negatively correlated with refracture after PVP.Lower average CT values of posterior vertebral muscle group and psoas major muscle are important influencing factors for refracture after PVP.关键词
骨质疏松性腰椎骨折/经皮椎体成形术/再骨折/相关性Key words
Osteoporotic lumbar fracture/Percutaneous vertebroplasty/Refracture/correlation分类
临床医学引用本文复制引用
刘祖耀,李强,李富,张洪剑,杨等,吕朝辉..椎旁肌CT值与骨质疏松性腰椎骨折患者经皮椎体成形术后再骨折的关系[J].转化医学杂志,2025,14(3):50-55,6.基金项目
2022年首都卫生发展科研专项重点攻关项目(2022-1-7032) （2022-1-7032）
