转化医学杂志2025，Vol.14Issue(1)：88-93,6.DOI:10.3639/i.issn.2095-3097.2025.01.019
重症患者发生肾功能亢进的危险因素分析
Analysis of Risk Factors for Augmented Renal Clearance in Critically Ill Patients
摘要
Abstract
Objective To explore the risk factors for augmented renal clearance(ARC)in critically ill patients.Methods A retrospective analysis was conducted on 170 critically ill patients admitted to the Department of Critical Care Medicine,Huangshan City People's Hospital from June 2021 to February 2022.Basic information on ICU admission and relevant clinical data during treatment were collected.Patients were divided into the ARC and non-ARC group based on whether ARC occurred.Univariate analysis and Logistic regression analysis were employed to identify the potential risk factors affecting ARC.Results Univariate analysis demonstrated that 43(25.3%)patients were diagnosed with ARC.Disease type,age,body mass index(BMI),the Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)score,the Nutrition Risk in Critically Ill(NUTRIC)score,C-reactive protein(CRP),albumin(Alb),serum creatinine(SCr),and blood urea nitrogen(BUN)on ICU admission were associated with ARC.Multivariate analysis indicated that trauma(OR=3.378,95%CI:1.615-7.067;P=0.001),age(OR=0.935,95%CI:0.906-0.965;P<0.01),and SCr on ICU admission(OR=0.983,95%CI:0.972-0.995;P<0.004)were risk factors for ARC in critically ill patients.Conclusion Trauma,age,and SCr on ICU admission are risk factors for ARC in critically ill patients.关键词
重症患者/肾功能亢进/危险因素/创伤/年龄/血肌酐Key words
Critically ill patients/Augmented renal clearance/Risk factors/Trauma/Age/Serum creatinine分类
医药卫生引用本文复制引用
毕昱,洪曦菲,汪健蕾,郑绍鹏..重症患者发生肾功能亢进的危险因素分析[J].转化医学杂志,2025,14(1):88-93,6.基金项目
安徽省2021医疗卫生重点专科建设项目(2021) （2021）
黄山市第五批市"特支计划"创新领军人才科研基金项目(黄人才办[2020]3号) （黄人才办[2020]3号）
