Abstract
Objective To investigate the correlation between bone mineral density and paravertebral muscle degeneration in female patients with vertebral fracture.Methods This prospective study included 128 patientswith vertebral fracture(study group)who received treatment from October 2022 to July 2024,and 128 volunteers(control group)who underwent physical examination during the same period.Paravertebral muscle degeneration,magnetic resonance imaging(MRI)-based vertebral bone quality(VBQ)score and bone density were compared between groups.The correlation between bone mineral density(BMD)and MRI-VBQ score and paravertebral muscle degeneration was analyzed.Results There was no statistical significance in the degree of L3 and L4 lumbar muscle between groups(P>0.05).The ratio of L3 multifidus/erector spine muscle(t=7.243,P=0.000),L3 steatosis(t=46.607,P=0.000),L4 multifidus/erector spine muscle(t=9.269,P=0.000),L4 steatosis ratio(t=39.809,P=0.000)in the study group were significantly higher than those of the control group.L3 vertebral length/lumbar indentation value(t=13.237,P=0.000),L3 fat thickness/lumbar indentation value(t=43.930,P=0.000),L4 vertebral length/lumbar indentation value(t=10.983,P=0.000),L4 fat thickness/lumbar indentation value(t=69.119,P=0.000)in the study group were significantly lower than those of the control group.The MRI vertebral bone mass score(t=3.249,P=0.001)in the study group was significantly higher than that of the control group.BMD of femoral neck(t=13.231,P=0.000)and lumbar L1-4(t=28.776,P=0.000)in the study group were significantly lower than that of control group.There was no statistical significance in the degree of lumbar muscle at L3 and L4 between groups(P>0.05).L3 polyfidus/erector spine(t=9.407,P=0.000),L3 steatosis ratio(t=17.950,P=0.000),L4 polyfidus/erector spine(t=13.796,P=0.000),L4 steatosis ratio(t=3.737,P=0.000)in the study group were singificantly higher than those of the control group.L3 vertebral length/lumbar indentation value(t=223.641,P=0.000),L3 fat thickness/lumbar indentation value(t=7.707,P=0.000),L4 vertebral length/lumbar indentation value(t=112.980,P=0.000,P=0.000),L4 fat thickness/lumbar indentation value(t=17.214,P=0.000)in the study group were significantly lower than those of the control group.MRI-based vertebral bone mass score(t=3.599,P=0.000)in the study group was significantly higher than that of the control group.Femoral neck(t=19.222,P=0.000)in the study group was significantly higher than that of control group.Bone mineral density(BMD)of lumbar spine L1-4(t=65.846,P=0.000)was significantly lower than that of osteopenia group.Through correlation analysis,MRI vertebral bone mass score,L3 multifidus/erector spine muscle,L3 steatosis ratio,L4 multifidus/erector spine muscle,L4 steatosis were negatively correlated with femoral neck BMD and L1-4 BMD.L3 vertebral length/lumbar indentation value,L3 fat thickness/lumbar indentation value,L4 vertebral length/lumbar indentation value,L4 fat thickness/lumbar indentation value were positively correlated with femoral neck BMD and L1-4 BMD.Conclusion Bone mineral density is significantly correlated with paravertebral muscle degeneration in female vertebral fracture patients,which can be used as an important basis for clinical diagnosis and prognosis.关键词
椎体骨折/骨密度/椎旁肌肉退变/相关性Key words
Vertebral fracture/Bone density/Paravertebral muscle degeneration/Correlation分类
临床医学
