中国猪业2025，Vol.20Issue(2)：35-50,16.DOI:10.16174/j.issn.1673-4645.2025.02.003
基因编辑技术在猪分子育种中的研究进展与前景展望
Research Progress and Prospect of Gene Editing Technology in Pig Molecular Breeding
摘要
Abstract
As one of the earliest domesticated species,the breeding improvement of pigs had always been the core driving force for the development of the pig industry.Compared with the drawbacks of traditional pig breeding,such as long breeding cycles and low effi-ciency in trait screening,gene-editing technology could precisely locate target gene loci,achieve targeted improvement of various e-conomic traits such as growth and development,disease resistance,and reproductive traits,and significantly enhance the efficiency of pig breeding.Moreover,in the current challenging context of traditional breeding,the application of gene-editing technology also helped to address the challenges faced in China's pig production.However,due to the wide variety of gene-editing technologies with different principles,there was a relatively high technical threshold.Therefore,this paper systematically summarized the working princi-ples,main types,and application status of current gene-editing technologies,and discussed and analyzed biological and ethical safety issues as well as the current opportunities and challenges.On the premise of ensuring biological safety,it provided certain refer-ences for guaranteeing the safe supply of meat and promoting the leap-forward development of China's pig breeding industry,and promoting the leapfrog development of China's pig breeding industry.关键词
基因编辑/猪/分子育种/应用/发展前景/抗病能力/繁殖性状Key words
gene editing technology/pig/molecular breeding/application/development prospects/disease resistance/reproductive traits分类
畜牧业引用本文复制引用
李云蕾,叶凯文,熊明福,李健,刘亚星,李超程,孔思远,张永生..基因编辑技术在猪分子育种中的研究进展与前景展望[J].中国猪业,2025,20(2):35-50,16.基金项目
兵团科技计划项目(KC2024CC007) （KC2024CC007）
自治区科技支疆项目计划(2022E02138) （2022E02138）
石河子大学高层次人才科研启动项目(2022ZK022) （2022ZK022）
