中西医结合肝病杂志2025，Vol.35Issue(4)：406-409,4.DOI:10.3969/j.issn.1005-0264.2025.004.003
通阳祛湿方治疗非酒精性脂肪性肝病的临床疗效分析
Clinical efficacy analysis of Tongyang dampness removal formula in the treatment of nonalcoholic fatty liver disease
摘要
Abstract
Objective:The objective was to evaluate the clinical efficacy of Tongyang Qushi Fang in patients with nonalcoholic fatty liver disease(NAFLD).Methods:130 patients with NAFLD were randomly divided into the control group(62 cases)and the treatment group(68 cases).The control group received simple weight control,while the treatment group was given Tongyang Qushi Fang in addition to the routine treatment provided to the control group.Results:After 24 weeks of treatment,both groups showed a significant reduction in TCM syndrome scores,liver-spleen CT ratio,body weight,and BMI(P＜0.05).The treatment group showed a better decrease in TCM syndrome scores compared to the control group(P＜0.05).The liver-spleen CT ratio improved in both groups,with statistically significant differences(P＜0.05)The improvement of biochemical indexes such as alanine aminotransferase(ALT),aspartate aminotransferase(AST),glutamyl transpeptidase(GGT),alkaline phosphatase(Alp),total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein(LDL-C)and glycated hemoglobin(HbA1c)in the treatment group was superior to that in the control group(P＜0.05).Conclusion:Tongyang Qushi Fang can improve the clinical efficacy in patients with cold-dampness-trapped spleen type NAFLD.关键词
通阳祛湿方/非酒精性脂肪性肝病/寒湿困脾Key words
Tongyang Qushi Fang/non-alcoholic fatty liver disease/cold-dampness-trapped spleen分类
医药卫生引用本文复制引用
孙汇,郭丽颖,贾建伟,苗静..通阳祛湿方治疗非酒精性脂肪性肝病的临床疗效分析[J].中西医结合肝病杂志,2025,35(4):406-409,4.基金项目
国家自然科学基金面上项目(No.82274424),全国名老中医药专家传承工作室建设项目,中国肝炎防治基金会中西医肝病基金课题(No.YGFK20210022) （No.82274424）
