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Death domain-associated protein(Daxx)impairs colon cancer chemotherapy by inhibiting the cGAS-STING pathway

XI ZHU KAI HUANG XIAOMING KAO ZHAOHUI TANG WENJIE GUO TIANCONG WU QIURONG LI

Oncology Research2025，Vol.33Issue(5)：P.1149-1159,11.

Oncology Research2025，Vol.33Issue(5)：P.1149-1159,11.DOI:10.32604/or.2024.054930

Death domain-associated protein(Daxx)impairs colon cancer chemotherapy by inhibiting the cGAS-STING pathway

XI ZHU ¹KAI HUANG ²XIAOMING KAO ³ZHAOHUI TANG ²WENJIE GUO ²TIANCONG WU ⁴QIURONG LI¹

作者信息

1. Research Institute of General Surgery,Jinling Hospital,Nanjing Medical University,Nanjing,210002,China Research Institute of General Surgery,Nanjing Jinling Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing,210002,China
2. State Key Laboratory of Pharmaceutical Biotechnology,School of Life Science,Nanjing University,Nanjing,210093,China
3. Research Institute of General Surgery,Nanjing Jinling Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing,210002,China
4. Department of Radiation Oncology,Nanjing Jinling Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing,210002,China
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摘要

关键词

Death domain-associated protein(Daxx)/Stimulator of the interferon gene(STING)/Colorectal cancer(CRC)/Chemotherapy

分类

医药卫生

引用本文复制引用

XI ZHU,KAI HUANG,XIAOMING KAO,ZHAOHUI TANG,WENJIE GUO,TIANCONG WU,QIURONG LI..Death domain-associated protein(Daxx)impairs colon cancer chemotherapy by inhibiting the cGAS-STING pathway[J].Oncology Research,2025,33(5):P.1149-1159,11.

基金项目

supported by the National Natural Science Foundation of China(82202956)。（82202956）

Oncology Research

ISSN：0965-0407

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