首页|期刊导航|Neural Regeneration Research|Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model:Single-cell RNA sequencing analysis

Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model:Single-cell RNA sequencing analysis

Tangxing Jiang Yaning Li Hehui Liu Yijun Sun Huidan Zhang Qirui Zhang Shuyao Tang Xu Niu Han Du Yinxia Yu Hongwei Yue Yunyun Guo Yuguo Chen Feng Xu

Neural Regeneration Research2026，Vol.21Issue(2)：P.742-755,14.

Neural Regeneration Research2026，Vol.21Issue(2)：P.742-755,14.DOI:10.4103/NRR.NRR-D-24-01269

Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model:Single-cell RNA sequencing analysis

Tangxing Jiang ¹Yaning Li ¹Hehui Liu ¹Yijun Sun ¹Huidan Zhang ¹Qirui Zhang ¹Shuyao Tang ¹Xu Niu ¹Han Du ¹Yinxia Yu ¹Hongwei Yue ¹Yunyun Guo ¹Yuguo Chen ¹Feng Xu¹

作者信息

1. Department of Emergency Medicine,Qilu Hospital of Shandong University,Jinan,Shandong Province,China Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine,Institute of Emergency and Critical Care Medicine of Shandong University,Chest Pain Center,Qilu Hospital of Shandong University,Jinan,Shandong Province,China Medical and Pharmaceutical Basic Research Innovation Center of Emergency and Critical Care Medicine,China’s Ministry of Education,Shandong Provincial Engineering Laboratory for Emergency and Critical Care Medicine,Key Laboratory of Emergency and Critical Care Medicine of Shandong Province,Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Shandong Province,Qilu Hospital of Shandong University,Jinan,Shandong Province,China NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug,Qilu Hospital of Shandong University,Jinan,Shandong Province,China National Key Laboratory for Innovation and Transformation of Luobing Theory,The Key Laboratory of Cardiovascular Remodeling and Function Research,Chinese Ministry of Education,Chinese National Health Commission and Chinese Academy of Medical Sciences,Qilu Hospital of Shandong University,Jinan,Shandong Province,China
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摘要

关键词

Blood-brain barrier disruption/cardiac arrest/hippocampus/microglia/neuroinflammation/neuroprotection/neutrophil/oligodendrocyte dysfunction/S100A8/single-cell RNA sequencing

分类

医药卫生

引用本文复制引用

Tangxing Jiang,Yaning Li,Hehui Liu,Yijun Sun,Huidan Zhang,Qirui Zhang,Shuyao Tang,Xu Niu,Han Du,Yinxia Yu,Hongwei Yue,Yunyun Guo,Yuguo Chen,Feng Xu..Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model:Single-cell RNA sequencing analysis[J].Neural Regeneration Research,2026,21(2):P.742-755,14.

基金项目

supported by the National Science Foundation of China,Nos.82325031(to FX),82030059(to YC),82102290(to YG),U23A20485(to YC) （to FX）

Noncommunicable Chronic Diseases-National Science and Technology Major Project,No.2023ZD0505504(to FX),2023ZD0505500(to YC) （to FX）

the Key R&D Program of Shandong Province,No.2022ZLGX03(to YC). （to YC）

Neural Regeneration Research

ISSN：1673-5374

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