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SLFN11 Deficiency-Induced Gemcitabine Resistance Is Overcome by Agents Targeting the DNA Damage Response in Pancreatic Cancer Cells

Jae Hyeong Kim Yuna Youn Jin-Hyeok Hwang

BIOCELL2025，Vol.49Issue(4)：P.681-700,20.

BIOCELL2025，Vol.49Issue(4)：P.681-700,20.DOI:10.32604/biocell.2025.062144

SLFN11 Deficiency-Induced Gemcitabine Resistance Is Overcome by Agents Targeting the DNA Damage Response in Pancreatic Cancer Cells

Jae Hyeong Kim ¹Yuna Youn ¹Jin-Hyeok Hwang²

作者信息

1. Department of Internal Medicine,Seoul National University Bundang Hospital,Seongnam-si,13620,Gyeonggi-do,Republic of Korea
2. Department of Internal Medicine,Seoul National University Bundang Hospital,Seongnam-si,13620,Gyeonggi-do,Republic of Korea Department of Internal Medicine,Seoul National University College of Medicine,Seoul,03080,Republic of Korea
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摘要

关键词

SLFN11/DNA-damaging agents/DNA damage response/pancreatic cancer

分类

医药卫生

引用本文复制引用

Jae Hyeong Kim,Yuna Youn,Jin-Hyeok Hwang..SLFN11 Deficiency-Induced Gemcitabine Resistance Is Overcome by Agents Targeting the DNA Damage Response in Pancreatic Cancer Cells[J].BIOCELL,2025,49(4):P.681-700,20.

基金项目

supported by the 8th AstraZeneca-KHIDI(Korea Health Industry Development Institute)oncology research program （Korea Health Industry Development Institute）

a research grant was supported by AstraZeneca and by Grant No.02-2022-0020 from the Seoul National University Hospital(SNUBH)Research Fund. （SNUBH）

BIOCELL

ISSN：0327-9545

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