长春中医药大学学报2025，Vol.41Issue(4)：415-419,5.DOI:10.13463/j.cnki.cczyy.2025.04.014
甲型流感病毒与COVID-19患者血常规差异分析
Analysis of differences in blood routine parameters in patients infected with influenza A virus and Corona Virus Disease 2019
摘要
Abstract
Objective To evaluate the effect of influenza A virus and Corona Virus Disease 2019(COVID-19)on white blood cell count and blood routine parametes,providing insights for guiding clinical medication.Influenza A virus and COVID-19 had similar clinical features,but their pathogenic mechanisms were different.Few studies compared their effect on blood parameters.Methods This study collected blood routine and C-reactive protein(CRP)data from patients with influenza A and CO VID-19 in Guangzhou First People's Hospital(2022-2023).Among them,there were 222 patients with influenza A,186 patients with COVID-19,and 100 people in the control group.CRP data included 146 patients with influenza A and 149 patients with CO VID-19.Data were analyzed with t-test and Kruskal-Wallis test.Results In patients with influenza A,the total white blood cell count,absolute value and percentage of monocytes,percentage of eosinophils and basophils,total red blood cell count,platelet count,and hemoglobin and reticulocyte counts were higher,but percentage of neutrophils and reticulocytes,and CRP level were lower than those in patients with COVID-19.There were statistically significant differences in white blood cell count,platelet count,neutrophil count and percentage,and monocyte count and percentage among three groups(P＜0.05).Conclusion Compared with the blood routine parameters and CRP levels between CO VID-19 and influenza A patients,the patients with influenza A have higher white blood cell and monocyte counts,indicating a stronger immune response.The platelet counts of both infections are lower than those of the control group,with COVID-19 showing the lowest platelet count,possibly due to effect of immune system.Reticulocyte counts are lower in both infections,with COVID-19 showing the lowest,indicating bone marrow impairment.CRP level of influenza A is lower than that of CO VID-19,indicating the presence of inflammation and potential bacterial co-infection in CO VID-19 cases.关键词
甲型流感病毒/COVID-19/血常规/白细胞计数Key words
influenza A virus/Corona Virus Disease 2019/routine blood parameters/white blood cell count分类
基础医学引用本文复制引用
张娟,徐邦牢,李伟杰,杨娜..甲型流感病毒与COVID-19患者血常规差异分析[J].长春中医药大学学报,2025,41(4):415-419,5.基金项目
国家自然科学基金项目(8160111347) （8160111347）
广州市科技计划项目(202201020240) （202201020240）
