大学化学2025，Vol.40Issue(5)：376-382,7.DOI:10.12461/PKU.DXHX202411055
绿色制药背景下的安息香氧化实验教学改革
Teaching Reform of Benzoin Oxidation Experiment in the Context of Green Pharmaceutical Chemistry
摘要
Abstract
Green chemistry has emerged as a pivotal focus in organic synthesis and pharmaceutical development.This paper introduces a photocatalytic benzoin oxidation experiment grounded in green chemistry principles.The experiment utilizes oxygen from the air as the oxidant,9-mesityl-10-methylacridinium perchlorate as the photocatalyst,triethylenediamine as the base,and chloroform as the solvent,subjected to irradiation by a 456 nm LED for 2 h.By optimizing the experimental conditions,we established the optimal reaction parameters,which were subsequently implemented in undergraduate laboratory courses,thereby integrating scientific research with education.关键词
绿色有机化学/光催化/安息香氧化/本科教学实验Key words
Green organic chemistry/Photocatalysis/Benzoin oxidation/Undergraduate teaching experiment分类
教育学引用本文复制引用
罗美虹,王洪玉..绿色制药背景下的安息香氧化实验教学改革[J].大学化学,2025,40(5):376-382,7.基金项目
国家自然科学基金-面上项目(22377113) （22377113）
中国海洋大学本科教育教学研究项目(2024JY069) （2024JY069）
