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Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression

Amit Kumar Chakraborty Marilia Takada Bikash Sahay Vikas Kumar Manish V.Bais Rajnikant Dilip Raut Kisa Iqbal Chumki Choudhury Thabet Alhousami Sami Chogle Alexa S.Acosta Lana Fagman Kelly Deabold

国际口腔科学杂志（英文版）2025，Vol.17Issue(2)：206-220,15.
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国际口腔科学杂志（英文版）2025，Vol.17Issue(2)：206-220,15.DOI:10.1038/s41368-025-00363-x

Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression

Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression

Amit Kumar Chakraborty 1Marilia Takada 2Bikash Sahay 2Vikas Kumar 3Manish V.Bais 1Rajnikant Dilip Raut 1Kisa Iqbal 4Chumki Choudhury 1Thabet Alhousami 5Sami Chogle 6Alexa S.Acosta 2Lana Fagman 2Kelly Deabold2

作者信息

  • 1. Department of Translational Dental Medicine,Boston University Henry M.Goldman School of Dental Medicine,Boston,USA
  • 2. College of Veterinary Medicine,University of Florida,Gainesville,USA
  • 3. Dept.of Biochemistry and Molecular Biotechnology,University of Massachusetts Chan Medical School,Shrewsbury,USA
  • 4. Department of Translational Dental Medicine,Boston University Henry M.Goldman School of Dental Medicine,Boston,USA||Department of Endodontics,Henry M.Goldman School of Dental Medicine,Boston University,Boston,USA
  • 5. Department of Translational Dental Medicine,Boston University Henry M.Goldman School of Dental Medicine,Boston,USA||Department of Endodontics,Henry M.Goldman School of Dental Medicine,Boston University,Boston,USA||Department of Basic and Clinical Oral Sciences,Faculty of Dentistry,Umm Al-Qura University,Makkah,Saudi Arabia
  • 6. Department of Endodontics,Henry M.Goldman School of Dental Medicine,Boston University,Boston,USA
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摘要

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Amit Kumar Chakraborty,Marilia Takada,Bikash Sahay,Vikas Kumar,Manish V.Bais,Rajnikant Dilip Raut,Kisa Iqbal,Chumki Choudhury,Thabet Alhousami,Sami Chogle,Alexa S.Acosta,Lana Fagman,Kelly Deabold..Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression[J].国际口腔科学杂志（英文版）,2025,17(2):206-220,15.

基金项目

The authors acknowledge NIH/NIDCR grant R01 DE031413 and CTSA pilot grant UL1TR001430 to Manish V.Bais. （）

国际口腔科学杂志（英文版）

1674-2818

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