国际医药卫生导报2025，Vol.31Issue(9)：1421-1425,5.DOI:10.3760/cma.j.cn441417-20241225-09003
骨水泥/椎体体积比与经皮椎体成形术后邻近椎体压缩骨折的相关性分析
Correlation analysis between bone cement/vertebral body volume ratio and adjacent vertebral compression fractures after percutaneous vertebroplasty
摘要
Abstract
Objective To analyze the correlation between bone cement/vertebral body volume ratio and adjacent vertebral compression fractures(AVCF)after percutaneous vertebroplasty(PVP).Methods The clinical data of 202 patients with osteoporotic vertebral compression fracture treated by PVP from June 2018 to June 2022 in the Department of Spinal Surgery of Shaanxi Provincial Rehabilitation Hospital were retrospectively analyzed,including 89 males and 113 females,with an age of 56-78(67.98±6.93)years old,followed up for 6-12(8.32±2.31)months.According to whether AVCF occurred after operation,the patients were divided into an AVCF group(31 cases)and a non-AVCF group(171 cases).Univariate and multivariate logistic regression analysis were used to analyze on demographic data,body mass index,bone density,bone cement leakage,bone cement volume(BCV),larger vertebral body volume(LSBCV),vertebral body volume(VBV),BCV/VBV,LSBCV/VBV and other indicators for two groups.The receiver operator characteristic curve(ROC)was used to analyze the efficacies of influencing factors in predicting AVCF after PVP.Independent sample t test and x2 test were used for statistical analysis.Results Preoperative bone mineral density T value,LSBCV,LSBCV/VBV,and bone cement leakage had significant effects on AVCF after PVP(all P＜0.05).Multivariate logistic regression analysis showed that low preoperative bone mineral density(OR=0.377)and high LSBCV/VBV(OR=2.123)were independent risk factors for AVCF after PVP(both P＜0.05).The area under the curve(AUC)of preoperative bone mineral density in predicting the occurrence of AVCF after PVP was 0.638(0.559-0.746).The AUC of LSBCV/VBV was 0.800(0.723-0.877),and the optimal diagnostic threshold was 13.859％;the sensitivity,specificity,Youden index,positive predictive value,and negative predictive value of LSBCV/VBV in predicting the occurrence of AVCF after PVP were 83.87％,66.67％,0.505,31.33％,and 95.80％,respectively.Conclusion Low preoperative bone mineral density T value and high LSBCV/VBV are independent risk factors for AVCF after PVP,and LSBCV/VBV has certain predictive value for AVCF after PVP.关键词
经皮椎体成形术/邻近椎体压缩骨折/骨水泥/椎体体积比/相关性/受试者操作特征曲线Key words
Percutaneous vertebroplasty/Adjacent vertebral compression fractures/Bone cement/vertebral body volume ratio/Relevance/Receiver operator characteristic curve引用本文复制引用
杨月太,贾本治..骨水泥/椎体体积比与经皮椎体成形术后邻近椎体压缩骨折的相关性分析[J].国际医药卫生导报,2025,31(9):1421-1425,5.基金项目
陕西省2022年卫生健康科研项目(2022D012) 2022 Health Research Project of Shaanxi Province(2022D012) （2022D012）
