国际医药卫生导报2025，Vol.31Issue(9)：1475-1481,7.DOI:10.3760/cma.j.cn441417-20241113-09014
加速康复外科理念在肺癌围手术期的应用:一项基于随机对照试验的系统评价与meta分析
Application of enhanced recovery after surgery principles in the perioperative management of lung cancer:a systematic review and meta-analysis based on randomized controlled trials
摘要
Abstract
Objective This study aimed to systematically evaluate the impact of enhanced recovery after surgery(ERAS)principles on perioperative outcomes in patients undergoing lung cancer surgery.Methods Randomized controlled trials on the application effect of ERAS concept in the perioperative period of lung cancer were retrieved from databases such as PubMed,EMBASE,Cochrane Library,CNKI,Wanfang,and VIP from the establishment of the databases to July 2024,and the references included in the studies were traced.Medical subject headings and keywords were used to search.Meta-analysis was performed using STATA 16.0 software,and publication bias was assessed by funnel plot and Egger test.Results Finally,13 articles(1 719 patients)were included.The results of the meta-analysis showed that the incidence of postoperative complications in the ERAS group was lower than that in the control group(OR=0.33,95％CI:0.26-0.41,P＜0.01);the postoperative pain score of the ERAS group was lower than that of the control group(WMD=-1.04,95％CI:-1.46--0.61,P＜0.01);the retention time of the drainage tube in the ERAS group was shorter than that in the control group(WMD=-2.40,95％CI:-3.08--1.72,P＜0.01);the hospitalization time of the ERAS group was shorter than that of the control group(WMD=-3.51,95％CI:-4.33--2.68,P＜0.01).Conclusion Implementing ERAS principles in the perioperative management of lung cancer patients significantly reduces postoperative complication rates and pain levels and shortens both chest tube duration and hospital stay.关键词
加速康复外科/肺癌/围手术期/随机对照试验/Meta分析Key words
Enhanced recovery after surgery/Lung cancer/Perioperative period/Randomized controlled trial/Meta-analysis引用本文复制引用
吕晓东,高呈飞,赵金鹏..加速康复外科理念在肺癌围手术期的应用:一项基于随机对照试验的系统评价与meta分析[J].国际医药卫生导报,2025,31(9):1475-1481,7.基金项目
山东省自然科学基金青年项目(ZR2021QH062) The Youth Project of Natural Science Foundation of Shandong Province(ZR2021QH062) （ZR2021QH062）
