国际医药卫生导报2025，Vol.31Issue(10)：1620-1623,4.DOI:10.3760/cma.j.cn441417-20241211-10007
双扳机在拮抗剂方案中的应用进展
Research progress of dual trigger in GnRH antagonist protocol
摘要
Abstract
The trigger is a key step in the process of ovarian stimulation.It uses exogenous drugs to simulate or induce the endogenous luteinizing hormone surge,promoting the final maturation of oocytes,resumption of meiosis,and triggering ovulation.It determines the outcomes of in vitro fertilization/intracytoplasmic sperm injection.The dual trigger is to promote the final maturation of the oocyte using gonadotropin-releasing hormone agonist and human chorionic gonadotropin,and is mostly used in the GnRH antagonist protocol.Dual trigger can improve oocyte quality and clinical pregnancy rates in poor and normal ovarian response populations,also reduce the risk of moderate/severe ovarian hyperstimulation syndrome,and offer the possibility of fresh embryo transfer cycle in high ovarian response populations.This article reviews the role of the dual trigger in the GnRH antagonist protocol.关键词
辅助生殖技术/双扳机/拮抗剂/临床妊娠/体外受精/胞浆内单精子注射/进展Key words
Assisted reproductive technology/Dual trigger/Antagonist/Clinical pregnancy/In vitro fertilization/intracytoplasmic sperm injection/Progress引用本文复制引用
于涵煦,范艳茹,朱明青,刘雪梅..双扳机在拮抗剂方案中的应用进展[J].国际医药卫生导报,2025,31(10):1620-1623,4.基金项目
山东省自然科学基金(ZR2021MH012) Natural Science Foundation of Shandong Province(ZR2021MH012) （ZR2021MH012）
