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血清游离脂肪酸、脂联素与糖尿病视网膜病变的关系

司艳艳 刘圣勋

国际医药卫生导报2025,Vol.31Issue(10):1706-1708,3.
国际医药卫生导报2025,Vol.31Issue(10):1706-1708,3.DOI:10.3760/cma.j.cn441417-20240319-10025

血清游离脂肪酸、脂联素与糖尿病视网膜病变的关系

Relationship of serum levels of nonestesterified fatty acid and adiponectin with diabetic retinopathy

司艳艳 1刘圣勋1

作者信息

  • 1. 滨州医学院附属医院检验科,滨州 256600
  • 折叠

摘要

Abstract

Objective To investigate the relationship of serum levels of adiponectin(ADPN)and nonestesterified fatty acid(NEFA)with diabetic retinopathy(DR).Methods Thirty-four patients with type 2 diabetes mellitus(T2DM)treated at Binzhou Medical University Hospital from November 2021 to May 2022 were selected as the study objects,including 18 males and 16 females who were 36-75 years old.According to whether they had DR,the patients were divided into a non-DR group(18 cases)and a DR group(16 cases).Sixteen healthy examinees taking physical examination at Binzhou Medical University Hospital during the same period were selected as a health control group,including 9 males and 7 females who were 33-74 years old.The levels of NEFA,ADPN,blood glucose,cholesterol(CHO),low-density lipoprotein(LDL),triglyceride(TG),and high-density lipoprotein(HDL)in all the subjects were detected.t test was used for the statistical analysis.Results The levels of NEFA and ADPN in the DR group were(1.03±0.38)mmol/L and(5.64±1.57)mg/L,the levels in the non-DR group(0.47±0.13)mmol/L and(7.99±1.98)mg/L,and the levels in the healthy control group(0.47±0.13)mmol/L and(7.99±1.98)mg/L,with statistical differences(both P<0.05).Conclusion Serum levels of SNEFA and ADPN are associated with DR in patients with T2DM.

关键词

2型糖尿病/血清游离脂肪酸/脂联素/视网膜病变

Key words

Type 2 diabetes mellitus/Nonestesterified fatty acid/Adiponectin/Retinopathy

引用本文复制引用

司艳艳,刘圣勋..血清游离脂肪酸、脂联素与糖尿病视网膜病变的关系[J].国际医药卫生导报,2025,31(10):1706-1708,3.

基金项目

山东省医药卫生基金(2017WS369) Shandong Medical and Health Foundation(2017WS369) (2017WS369)

国际医药卫生导报

1007-1245

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