国际医药卫生导报2025,Vol.31Issue(10):1706-1708,3.DOI:10.3760/cma.j.cn441417-20240319-10025
血清游离脂肪酸、脂联素与糖尿病视网膜病变的关系
Relationship of serum levels of nonestesterified fatty acid and adiponectin with diabetic retinopathy
摘要
Abstract
Objective To investigate the relationship of serum levels of adiponectin(ADPN)and nonestesterified fatty acid(NEFA)with diabetic retinopathy(DR).Methods Thirty-four patients with type 2 diabetes mellitus(T2DM)treated at Binzhou Medical University Hospital from November 2021 to May 2022 were selected as the study objects,including 18 males and 16 females who were 36-75 years old.According to whether they had DR,the patients were divided into a non-DR group(18 cases)and a DR group(16 cases).Sixteen healthy examinees taking physical examination at Binzhou Medical University Hospital during the same period were selected as a health control group,including 9 males and 7 females who were 33-74 years old.The levels of NEFA,ADPN,blood glucose,cholesterol(CHO),low-density lipoprotein(LDL),triglyceride(TG),and high-density lipoprotein(HDL)in all the subjects were detected.t test was used for the statistical analysis.Results The levels of NEFA and ADPN in the DR group were(1.03±0.38)mmol/L and(5.64±1.57)mg/L,the levels in the non-DR group(0.47±0.13)mmol/L and(7.99±1.98)mg/L,and the levels in the healthy control group(0.47±0.13)mmol/L and(7.99±1.98)mg/L,with statistical differences(both P<0.05).Conclusion Serum levels of SNEFA and ADPN are associated with DR in patients with T2DM.关键词
2型糖尿病/血清游离脂肪酸/脂联素/视网膜病变Key words
Type 2 diabetes mellitus/Nonestesterified fatty acid/Adiponectin/Retinopathy引用本文复制引用
司艳艳,刘圣勋..血清游离脂肪酸、脂联素与糖尿病视网膜病变的关系[J].国际医药卫生导报,2025,31(10):1706-1708,3.基金项目
山东省医药卫生基金(2017WS369) Shandong Medical and Health Foundation(2017WS369) (2017WS369)