湖南中医药大学学报2025，Vol.45Issue(4)：654-661,8.DOI:10.3969/j.issn.1674-070X.2025.04.010
厚朴饮片质量等级标准综合评分机制研究
Comprehensive scoring mechanism of quality grade standard of Houpo Decoction-ready Medicines
摘要
Abstract
Objective To analyze the quality of Houpo Decoction-ready Medicines based on various data analysis softwares,and to establish a comprehensive scoring mechanism for the quality grade standard of decoction-ready medicines.Methods Measure was made on 17 batches of Houpo Decoction-ready Medicines from the market for their appearance traits,alcohol extract,ash,magnolol,honokiol,syringin,magnoliine,and volatile components.SPSS 23.0 software was used for correlation analysis of the data,combined with SIMCA 14.1 software for principal component analysis and orthogonal partial least squares discriminant analysis(OPLS-DA)to screen the difference indexes affecting their quality.The comprehensive quality grade evaluation system of Houpo Decoction-ready Medicines was established using the analytic hierarchy process combined with K-value cluster analysis.Results Statistical analysis of the collected index data finds out that the difference indexes of Houpo(Magnolia Officinalis)were determined as L*,b*,magnolol,and extract.Houpo Decoction-ready Medicines could be divided into three grades in accordance with the total scores with the first grade＞110 points,the second grade 90-110 points,and the third grade＜90 points.Conclusion The established comprehensive scoring mechanism can effectively distinguish the quality of different Houpo Decoction-ready Medicines and provide scientific basis for the formulation of quality grade standards of decoction-ready medicines.关键词
厚朴/等级标准/主成分分析/正交偏最小二乘法判别分析/评分机制Key words
Houpo(Magnolia officinalis)/grade standard/principal component analysis/orthogonal partial least squares-discriminant analysis/scoring mechanism分类
中医学引用本文复制引用
阳睦贤,邹会品,肖明珠,贾瑶,张忠勤,周逸群,石继连..厚朴饮片质量等级标准综合评分机制研究[J].湖南中医药大学学报,2025,45(4):654-661,8.基金项目
湖南省自然科学基金项目(2023JJ50445) （2023JJ50445）
湖南振兴中药有限公司横向课题. （）
