湖南中医药大学学报2025，Vol.45Issue(4)：711-718,8.DOI:10.3969/j.issn.1674-070X.2025.04.019
基于多元统计分析和贝叶斯网络的精神分裂症合并超重或肥胖患者的中医证候分析
Chinese medicine pattern analysis of schizophrenic patients with overweight or obesity based on multivariate statistical analyses and Bayesian network
摘要
Abstract
Objective To investigate the Chinese medicine pattern laws in schizophrenia patients with overweight or obesity.Methods A cross-sectional study was conducted,collecting TCM pattern information of 360 schizophrenia patients with overweight or obesity who visited outpatient clinics or were hospitalized at the Third Hospital of Heilongjiang Province(Mental and Neurological Disease Hospital of Heilongjiang Province)and its sub-centers from June 2023 to June 2024.Multivariate statistical analyses,including factor analysis and cluster analysis,were employed for dimensionality reduction and categorization.Basic TCM pattern elements(disease location and nature)and pattern identification types were extracted and summarized.Bayesian network was used to preliminarily explore the relationships of patterns—pattern types—clinical index.Results Nine pattern factors and five pattern types were identified,with the affected organs involving the liver,gallbladder,heart,spleen,and kidney.Disease natures include qi deficiency,yang deficiency,phlegm,dampness,qi stagnation,blood stasis,qi deficiency,and fire-heat.The identified patterns include deficiency of the heart and spleen,dual deficiency of qi and yin,blood stasis due to qi deficiency,yang deficiency of the spleen and kidney,and dampness stagnation transforming into fire.When the target variable was set as the body mass index(BMI)≥24 kg/m2,the posterior probabilities for the patterns of yang deficiency of the spleen and kidney,deficiency of the heart and spleen,and dampness transforming into fire were the top three.Conclusion The TCM patterns in schizophrenia patients with overweight or obesity can be preliminarily categorized into five types.Among them,yang deficiency of the spleen and kidney,deficiency of the heart and spleen,and dampness transforming into fire are common patterns associated with higher BMI.Multivariate statistical analyses can be used to explore the pattern laws in schizophrenia patients with overweight or obesity.关键词
精神分裂症合并超重或肥胖/因子分析/聚类分析/多元统计分析/贝叶斯网络/中医证候Key words
schizophrenia with overweight or obesity/factor analysis/cluster analysis/multivariate statistical analysis/Bayesian network/Chinese medicine pattern分类
医药卫生引用本文复制引用
郑应康,陈星海,朱玺华,王涛,颉彦鹏,蔡萧君..基于多元统计分析和贝叶斯网络的精神分裂症合并超重或肥胖患者的中医证候分析[J].湖南中医药大学学报,2025,45(4):711-718,8.基金项目
黑龙江省中医药科研项目(ZHY2020054) （ZHY2020054）
黑龙江省博士后基金面上项目(LBH-Z22269) （LBH-Z22269）
黑龙江省青年人才托举工程项目(2022-QNRC1-30). （2022-QNRC1-30）
