湖南中医药大学学报2025，Vol.45Issue(4)：742-747,6.DOI:10.3969/j.issn.1674-070X.2025.04.024
从《医旨绪余》"种子之道"探讨卵巢储备功能减退合并复发性流产的证治思路
Pattern differentiation and treatment of diminished ovarian reserve complicated with recurrent spontaneous abortion based on"Way of Seeding"in Yi Zhi Xu Yu(Remnants of Medical Decree)
摘要
Abstract
Diminished ovarian reserve(DOR)and recurrent spontaneous abortion(RSA),as common gynecological reproductive endocrine disorders,exhibit potential pathological connections.In DOR patients,declining oocyte quality leads to an increased rate of embryonic aneuploidy,predisposing them to RSA.Conversely,the repeated pregnancy loss experienced by RSA patients induces stress responses that accelerate ovarian function decline.Both conditions adversely affect women's reproductive and mental health.The Ming Dynasty physician SUN Yikui,in the chapter of"Revised Traditional Folk Text on Fertility"of his medical treatise Yi Zhi Xu Yu(Remnants of Medical Decree),referred to the four principles of nourishing the uterus,nurturing sperms and ova,seizing the timing,and reinforcing deficiency as the"Way of Seeding",which is essential for successful conception.Guided by this theoretical framework,this paper holds that the pathogenesis of DOR complicated with RSA primarily involves kidney deficiency,accompanied by spleen deficiency,liver qi stagnation,and blood stasis.Therapeutic strategies focus on four aspects:optimizing the uterine environment,improving fertilized ovum quality,promoting regular ovulation,and implementing timely pregnancy maintenance.Through sequential pre-conception and post-conception interventions,integrating both tonifying and regulating therapies,and addressing the health of both men and women,this approach aims to reduce miscarriage rates and enhance fertility outcomes in DOR patients with RSA.关键词
卵巢储备功能减退/种子之道/复发性流产/脏腑辨证/卵巢功能Key words
diminished ovarian reserve/Way of Seeding/recurrent spontaneous abortion/pattern differentiation of zang-fu organs/ovarian function分类
医药卫生引用本文复制引用
舒畅,刘雁峰,邓楠,李晶晶,金凡惠,刘枳男,张璇..从《医旨绪余》"种子之道"探讨卵巢储备功能减退合并复发性流产的证治思路[J].湖南中医药大学学报,2025,45(4):742-747,6.基金项目
北京市自然科学基金面上项目(7222280) （7222280）
北京中医药大学研究生自主科研课题(ZJKT2023024). （ZJKT2023024）
