江苏大学学报（医学版）2025，Vol.35Issue(3)：238-244,7.DOI:10.13312/j.issn.1671-7783.y240160
狼疮性肾炎患者经皮肾穿刺活检术后血肿形成的危险因素分析
Analysis of risk factors for hematoma formation after percutaneous renal biopsy in patients with lupus nephritis
章菁 1郭琰 2沈伟 1陈群 1王世颖 1刘舒 1朱赟1
作者信息
- 1. 南京大学医学院附属鼓楼医院风湿免疫科,江苏 南京 210008
- 2. 江苏省军区南京第二十五离职干部休养所,江苏 南京 210004
- 折叠
摘要
Abstract
Objective:To investigate the risk factors for hematoma formation after ultrasound-guided percutaneous renal biopsy(PRB)in patients with lupus nephritis(LN).Methods:This retrospective study included 112 LN patients who underwent ultrasound-guided PRB at Nanjing Drum Tower Hospital between January 2023 and December 2024.Patients were divided into hematoma group(n=33)and non-hematoma group(n=79)based on ultrasound findings within one week after biopsy.The general characteristics,laboratory data,and postoperative pathological results after PRB were compared between the two groups,and the risk factors for hematoma formation after PRB were analyzed by Logistic regression.Results:Hematomas were observed in 33 patients,including 20 small,10 medium,and 3 large hematomas.There were statistically significant differences between the two groups in terms of a history of hypertension(P=0.002),chronic kidney disease(CKD)staging>stage 1(P=0.005),and activity index(AI)>5.5(P=0.003).Multivariate Logistic regression analysis confirmed hypertension(OR:3.110,95%CI:1.169-8.279,P=0.023),CKD staging>stage 1(OR:2.575,95%CI:1.043-6.362,P=0.040),and AI>5.5(OR:2.737,95%CI:1.076-6.691,P=0.034)were independent risk factors for hematoma formation.Conclusion:Hypertension,CKD staging>stage 1,and AI>5.5 may significantly increase the risk of hematoma formation after PRB.关键词
狼疮性肾炎/经皮肾穿刺活检/血肿/危险因素Key words
lupus nephritis/percutaneous renal biopsy/hematoma/risk factors分类
临床医学引用本文复制引用
章菁,郭琰,沈伟,陈群,王世颖,刘舒,朱赟..狼疮性肾炎患者经皮肾穿刺活检术后血肿形成的危险因素分析[J].江苏大学学报（医学版）,2025,35(3):238-244,7.
